Good afternoon Dr. Tortoriello,

I’m doing a fifth stimulated frozen embryo transfer due to thin lining issues and now have the best lining I’ve ever had of 8.7 mm, trilaminar. I expect to do my trigger injection tonight and start taking estrogen 2 mg daily with progesterone daily. My doctor said I have a choice of using progesterone suppository or PIO 50 mg injections daily but as the injection is best absorbed by the body she recommends the PIO injection to have a successful pregnancy.

My question is do you think that I could have too much progesterone in my body prior to transfer with PIO injections as I’m already producing my own progesterone? I want to do what’s best, and I’m reading some studies online that indicate too high levels of progesterone can reduce live birth rates. Thank you, Eliana G.