Ask Our Doctors

DearDr.Sher, Myselfandhusbandareboth38yrsoldstartedourfertilityjourneyattheageof32yrssotryingtoconceivefor6yrsnow. Westartedwithovulationinduction,hadanectopictreatedwithmethotrexate. LaterstartedwithIVFandnoticedIgetonlyfeweggs.Butmanagedtogetgoodqualityembryos.Didfreshtransferfailedtoimplant,didPGTAtestnormaleuploid2embryosoutof3,frozentransferfailedagai. HysteroscopydonefoundIhaveendometrialhyperplasiawithatypia.TreatedwithProgesteronefor3monthsclearedbutcomesbackagainandthentreatedwithmirenaIUDclearedin3monthsdidanotherfrozentransferbutfailedagain. RecentlyhadahysteroscopyandfoundthereisnoatypiaandIhavemirenabackinplace. IhavelowAMH,highBMI,andageof38yrsisnothelping.Istillhave1testednormalembryoandoneuntestedembryo. RecenttestalsofoundthatwearepartialmatchforDQAlphagenotyping. Whatsuggestionsyouhavetohelpusgetpregnant.Wedonothavemuchinformationaboutendometrialhyperplasia.pleasehelp.Wefeelwewalkintoanewproblemeverytimeweseeaspecialistbutarelookingforsomesolutionnow. MostofthespecialistaremoreworriedaboutmylowAMH.WhichisconcerningbuthavingendometrialhyperplasiaisalsoabiggerconcernIbelieve. Also,IusedtohaveregularnormalperiodsuntilIwas31yrs.Idonotwhathappenedatthattime,stresshasbeenapartandatthistimesincethenIhaveputonalotofweight. Iamdesperatelylookingforsomeoptions,suggestionsandhelpplease.Thanksforreadingthis. Couldyoupleasetellme

Hi there, We had a son nearly 5 years ago within a few months of trying (cesarian), since then we have had a blighted ovum, 1 chemical pregnancy, 1 6 week miscarriage trisomy 8, and 10 failed implantations (of high quality embryos). What would you recommend as next steps? We have had hysteroscopys to remove

Hi, I have RPL, and have 4 miscarriages this last year. Now done IVF with 13 eggs, 11 fertilized and only 2 made blasto at day 6. I have RA, mild endo. I take enbrel 50 mg 1xw and my ivf doctor now has me on 10mg prednisone. I had to freeze both embryo and

Dear Dr. Sher, do you have experience with the freeze of day 4 embryos (morulas)? My clinic is suggesting that we freeze all remaining embryos on day 4 after transfer on same day, because day 5 is a Sunday and they are not working. Because I missed the zygote state for freeze, the remaining options

Hi, I am ANA positive (as well as Smith (Sm) Ab, Sm RNP and Centromere B Ab Positive), I have had a chemical this year in March, a blighted ovum in June at 7 weeks, and then a MMC in September at 8 weeks. For the MMC I started lovenox a week after finding out

Hi Dr Sher, Im wanting to find out if you know of any doctors you have worked with, or share the same research and development knowledge as you do any in Cape Town. I live in Somerset West, near Stellenbosch but am willing to travel wherever.. I wish I could come see you in New

I’m at a bit of a loss. Having ICSI for secondary infertility (1st child conceived naturally age 29) and just midway through my 3rd cycle. I have paid up for a 4th cycle already so I’m keen to get some advice about what to change/ask for at my next appointment. cycle 1 – used Gonal-F

Hi Dr Sher, my name is Lindsay Tame. I recently heard you on a podcast and immediately recognized the South African accent. Im 42 years old and have done 3x IUI at Cape Fertility with Dr le Roux, 2x full rounds of ICSI and 2x ‘half’ rounds (stopping after aspiration due to the 1 egg

What could cause a day 7 BB blastocyst that was fertilized via ICSI to be haploid (PGT-A results)?

I want to donate eggs, I’ve done it before