Hi Dr. Sher, I’m 32 and am a Fragile X premutation carrier (90 repeats) with diminished ovarian reserve (AMH 0.44, on whatever scale the US uses). I just did my first stim cycle starting birth control on day 2 of my period and only taking it 5 days, then one day with no meds before starting microdose Lupron (20 units) twice a day for 3 days. On the third day of microdose Lupron I added 450 units Menopur and continued Menopur for 9 days adding Ganirelix for the last 4 days. Then triggered with 5,000 Pregnyl and 80 units Lupron. I had about 8 follicles growing a week in, and on the day of trigger they were 22, 18, 18, 11, 10, 10, and 9 mm. We hoped to get eggs from the 3 bigger follicles, and while 2 eggs were retrieved, neither were mature. I’m wondering what you would recommend we change from this protocol to have more success on our second try. Thanks!
FX DOR
By
Dr. Geoffrey Sher
/ March 11, 2024