I am 41.5 with DOR. I’m desperately looking for advice on what would be the right protocol. I don’t believe BC helps me. I had 2 months cancelled when on it for cysts. 1 estrogen producing and the other was not so aspirated and started with Protocol #2. I’ve also tried a lupron micro dose flare. I’m trying to do my own research and be my own advocate as I desperately want a child of my own. I’m also on a bunch of supplements in addition to levothyroxine and metformin and do acupuncture.
5/20/22
AMH .63
AFC between 8-15 depending on month
FSH 5.5
EST 56.6
Protocol 1/Egg Retrieval #1 March 2021 (1 month shy of 40)
29 days BC
3 days after stopping BC
stim day 1 (2/28/21)Follistim 225/Menopur 225 evenings
Dexamethasone 1mg by mouth at bedtime
3/4/21 Day 5 – Add Ganirelix
3/9/21 Day 10 – Azithromycin and 4mg Lupron trigger
3/12/21 Retrieval
Retrieved 6 (think there were close to 12, some empty)
Mature 4
Fertilized 4
Blasts 2
PGT-A 2 (both FETs failed, so started seeing a RI)
Protocol 2 – Cancelled
Antagonist with Growth Hormone
7/29 – 8/9 – Nuvaring
8/14-17 (stim day 1-4) – AM – 3 vials Menopur + 1mg Dexamethasone (stop when trigger)
PM – 3 vials Menopur + .35 Omnitrope
8/18-22 (stim day 5-9) AM AM – 3 vials Menopur + 1mg Dexamethasone (stop when trigger)
Add in Ganirelix before 6:30am daily
PM – 3 vials Menopur + .35 Omnitrope
Cancelled on 8/22 (stim day 9)
8/18
Progesterone-.70
LH-2.2
EST-137.3
Left – 9, 5, 3mm
Right – 16, 5, 4mm
8/20
Progesterone-.47
LH-1.1
EST-241.2
Left – 12, 8mm
Right – 20mm
8/22 (I chose to cancel cycle)
Progesterone-.46
LH-2.2
EST-383.6
Left – 16, 11mm
Right – 22, 6mm
Protocol 3 – Failed
Micro Dose Flare (Lupron) with Growth Hormone
9/6-9/26 BC (20 days)
10/1 clomid 100mg in evening for 5x nights
Lupron 20 every 12 hours and 1mg dexamethasone every morning until trigger
10/2-10/9 (stim day 1-8) AM- 2 vials Menopur + .35 Omnitrope + Lupron 20 + Dexa
PM – 300IU Gonal-F + Lupron 20 + Clomid 100mg
10/6 Labs/Ultrasound
Left – 11, 6, 5, 5mm
Right – 16, 12, 11, 11, 9, 8, 8, 7, 6, 4mm
LH – 10.1
Progesterone .53
Est – 426.4
10/8
Left – 12, 12, 12, 11, 7mm
Right – 13, 10mm
LH – 3.7
Progesterone .76
Est – 650.9
10/10
Left – 16, 11, 9, 7mm
Right – 29mm, 25mm, 21mm
LH – 4.1
Progesterone .73
Est – 1017.8
10/10 (stim day 9) Pregnyl Trigger 10,000 (stop melatonin)
10/11 Post Trigger Labs:
Progesterone – 2.5
LH – 1.4
10/12 Retrieval
Retrieved 6
Mature 2
Fertilized 0