Dear Dr. Sher:

Thank you for hosting this forum.

I am just shy of 41 with social infertility and have had two failed IVF cycles. The first used an antagonist protocol at 300 IU gonadotropin and resulted in one whole chromosome aneuploid blast. The second used estrogen-only priming, then 150 IU gonadotropin, but resulted in a lead follicle. Stims were restarted ten days after triggering and one whole chromosome blast resulted again.

I only have one more IVF cycle covered by my insurance left and my RE is planning on what sounds like a Lupron down regulation protocol. Does this sound appropriate for my case? All my numbers have been average for my age, so just outside DOR range. My last AMH a year ago was 1.14.

Also, eould you recommend any add-ons such as Omnitrope? My clinic does not use it but I’m getting other opinions before embarking on this last cycle.

Thank you.