Ask Our Doctors

Ask Our Doctors

Reproductive Immunology

Hello, I have had two, late, second trimester losses, back to back. Both of these losses have happened since I was diagnosed with a rare autoimmune, eosinophillic esophagitis. What is your familiarity with reproductive immunology and how likely is there a correlation between diagnosis of autoimmune disease and miscarriage?

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DOR,age,IVF

Hello, dear doctor. Listened to you podcast and been blown away by your expertise! I am a youthful 45 year old trying to get pregnant. Gotten pregnant 2 years ago naturally, but miscarried in week 9. Had done 3 IVF since. First with birth control, menopur (300 IU), cetrotide from day 4 stimm., HcG trigger.

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4th_ivf_cycle_questions_on_microdose_flare_protocol

Hello_Dr._Sher, I_am_42_yrs_old_with_a_low_AMH_(less_than_1)_trying_to_get_pregnant_for_the_2nd_time._My_first_pregnancy_was_natural_when_I_was_38._I_started_my_2nd_fertility_journey_with_IUI_where_we_discovered_endometritis_from_my_poorly_healed_C_section_scar._Since_clearing_that_up,_I_have_gone_through_3_rounds_of_IVF._Between_round_1_and_2,_I_got_pregnant_naturally,_but_miscarried_at_8_wks._In_round_2,_I_had_3_fertilized_eggs_2_that_reached_blastocyst_but_were_not_eupoloid_in_the_end._In_this_round_we_used_the_micro_dose_Lupron_protocol_but_with_out_birth_control_prior_to_starting._In_round_3_we_went_back_to_an_estrogen_patch_priming_protocol_which_resulted_in_lower_estrogen_levels_and_2_fertilized_eggs_that_did_not_make_it_past_the_blastocyst_stage. For_round_4_my_doctor_wants_to_do_the_microdose_flare_protocol_with_the_birth_control_for_8-12_days_before,_however_there_is_no_plan_to_overlap_the_BCP_with_a_GRH_agonist_as_you_have_suggested_in_your_online_information_on_factors_affecting_IVF_outcomes._Should_I_be_concerned_about_this?_Would_you_reccomend_a_different_protocol_instead? How_do_you_typcially_determine_the_number_of_days_on_bcp_before_starting_a_microdose_flare_protocol? _Do_you_monitor_FSH_and_LH_levels_at_the_start_and_during_the_BCP_period? Thank_you_in_advance_for_your_input. Also,_this_form_is_not_functioning_properly._I’ve_tried_typing_my_question_on_my_phone_and_my_computer_and_the_space_bar_has_been_disabled_on_both._Hence_the_underscore_spaces_between_words._You_may_want_your_IT_to_fix_this.

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estradiol

Can you kindly tell me what is the appropriate level of estradiol in a modified natural cycle? I am in the middle of a MN cycle. They had me take letrozole for 5 days and roughly 10 days later I had a lining that is 9.8 mm and trilaminar and follicle big enough to trigger

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