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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Page 6 of 68

Hormones & Ovulation Apr 27, 2025

TSH

Hello, I was wondering what the recommended parameters are for TSH level prior to FET. My most recent TSH level was 4.01, just wondering if these are good numbers for going into transfer. I’m 35 and low AMH(0.98). Just want… — Maria S.

Dr. Geoffrey Sher answered

Your elevated TSH could indicate an underlying hypothyyroid state which could be due to an autoimmune condition andf your low AMH points towards iminished ovarian reserve (DOR: 1. Thyroid Autoimmunity (TAI) & Immunologic Implantation Dysfunction (IID) Between 2% and 5% of women of the childbearing age have reduced…
Early Pregnancy & hCG Apr 27, 2025

To know much about my IVF journey

Thank you for receive me, what if my LH level is higher (15,45 mIU/ml on Day 3 of menstrual cycle — Paola U.

Dr. Geoffrey Sher answered

I would need much more information. If you would like to discuss your case with me , email my assistant (702-533-2691 and set up an online consultation with me,
Egg Health & Ovarian Reserve Apr 27, 2025

Empty folicals

Hi, I'm on my first round of ivf due to same sex relationship. Im from the UK. I have just had my first egg retrieval and I'm bitterly disappointed with the amount of egg they collected. I'm 37, amh 14.1,… — Katie M.

Dr. Geoffrey Sher answered

Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely to happen when multiple attempts are needed to retrieve an egg from a follicle, indicating the egg may have chromosomal abnormalities. The…
Ovarian Stimulation & OHSS Apr 10, 2025

FxPOI

Any advise would be appreciated for my 2 daughters recently diagnosed with fxpoi. 30 year old tried 2 cycles, the first down regulated before starting stims, range of doses were tried and a follicle slowly grew but was empty at… — Simone H.

Dr. Geoffrey Sher answered

I would need to consult directly with your daughters re ovarian stimulation. If you are interested, please reach outv to my assistant, Patti Converse (702-533-2691 ). Below is an article I wrote on Fragile-X FYI. Fragile X syndrome: Which IVF Candidates Should be Tested and How Should Results…
Early Pregnancy & hCG Apr 1, 2025

FET

Hi Dr Sher I’m 38 y/o and and going through fertility treatment using donor sperm. I have just had an unsuccessful fresh ICSI embryo transfer (6 eggs retrieved, 6 fertilised, grade A embryo transferred, 3 embryos frozen grades B B… — Liz D.

Dr. Geoffrey Sher answered

I Thank you for sharing your IVF treatment details. From what you’ve described, you are 38 years old and have recently undergone your second IVF cycle, during which three cleaved embryos of reasonable quality were transferred, but unfortunately, conception did not occur. In your first cycle, a single…
IVF Failure & Pregnancy Loss Apr 1, 2025

MOLAR PREGNANCY PREVENTION

MY WIFE HAD 2 CONSECUTIVE COMPLETE MOLAR PREGANANCIES AT AGE 24 AND 25. THEN SHE APPROACHED IVF, AND RETURNED A MALE EMBRYO BASED ON DR. SHER'S ARRICLE IN 2016 AS SOLUTION TO PREVENT A COMPLETE MOLE. MY QUESTION NOW, IS… — Ahmad A.

Dr. Geoffrey Sher answered

Not to my knowledge! Sorry! Geoff Sher
Uterine & Endometrial Health Apr 1, 2025

Sclerotherapy

I am looking for a clinic that can perform sclerotherapy for endometrioma treatment. Is this something that you offer? — Jessica L.

Dr. Geoffrey Sher answered

I don' think it is available presently. WE used to use Tetracycline hydrochloride 5%...cant get it any longer. Sorry! Geoff Sher
IVF Failure & Pregnancy Loss Mar 27, 2025

Cervix dilated

At20weeksinmyivfpregnacymycervixdilatedandledtostillbirth.what could be the reason — N R.

Dr. Geoffrey Sher answered

This sounds like cervical incompetence . You likely leaked fluids after the membranes ruptured and the fetus was infected. This is something that can be treated through the insertion of a cervical cerclage. Discuss it with your Obstetrician. Geoff Sher
Uterine & Endometrial Health Mar 21, 2025

U/S endometrium is 1.4 at day 4 of period

Dear Dr Sher, I live in Israel, am 40 years A old and having frozen embryo created with donor eggs as I have no ovarian reserve. No previous pregnancies or miscarriages. My endomerial lining measured on day 4 of my… — Ayelah B.

Dr. Geoffrey Sher answered

I need to have more information. An important consideration is "how long have you been estrogen-depleted". IOW how long have you been not having periods (amenorrhea). The reason I say this is that women who have been anesgtrogenic for >6moths, often have depletion of endometrial estrogen receptivity and…
Egg Health & Ovarian Reserve Mar 13, 2025

Failed Embyro transfer

Hi, I have low AMH. I have had 1 round of IVF and did not obtain any embyros. I had a second round of ICSI and obtained 3 embyros. From this round, I have had two Embyro transfers which did… — Tara B.

Dr. Geoffrey Sher answered

It is very likely that your issue is an embryo quality issue stemming from the egg. The egg rather than the sperm is the main determinant of embryo "competency". Women with diminished ovarian reserve are at at greater risk of poor egg quality if the protocol used for…
Hormones & Ovulation Mar 13, 2025

Hypothalamic amenorrhea

31 F/ G2 T0 P1 A1 L1/5’2.5 103lbs. Diagnosis: functional hypothalamic amenorrhea. DOR/PCOS/Lactational/thyroid all ruled out. Background: Past successful pregnancy with letrozol at 114lbs. Have been struggling with HA since then for 12 months. Past OBGYN wanted weight closer to… — Sarah O.

Dr. Geoffrey Sher answered

Women with HA can experience poorer egg quality. In addition, the low ovarian estrogen output can blunt endometrial response to estrogen. I advise you to have your doctor monitor endometrial thickness at the time of the hCG "trigger". It should measure at least 8mm. If less, this could…
IVF Failure & Pregnancy Loss Mar 11, 2025

RPL

I was excited to see the depth of understanding and research regardingRPL.i am having my third miscarriage at6-7weeks. Could I schedule a telehealth consult? — Jane M.

Dr. Geoffrey Sher answered

Absolutely you can. Email my assistant, Patti Converse at concierge@sherivf.com with your telephone # and she will call you right back and set this up. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure:…
Male Infertility Mar 10, 2025

MFI

Hi doctor Sher, You gave me two amazing children from your clinic. We are officially done with IVF but I would still like to grow my family naturally in hopes of a third child. Our only issue was MFI and… — Megan L.

Dr. Geoffrey Sher answered

Thanks! You made my day! I suggest you go online to www.proceptin.com and order Proceptin . It is the best fertility blend available in my opinion and is only available through the website. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at…
Uterine & Endometrial Health Mar 10, 2025

Adenomyosis

The best Protocol For Ivf With Adenomyosis? — Julia P.

Dr. Geoffrey Sher answered

There is no specific protocol for adenomyosis. It would depend on your clinical situation. I suggest yo email my assistant, Patti Converse (concierge@sherivf.com) and ask her to set you up with an online consultation with me to discuss our case in detail; Geoff Sher Adenomyosis: A Guide to…
Immunology & Implantation Mar 6, 2025

RIF

Dear dr Sher, I got my first child 2020 via embryodonation (34 yo) on the first attempt with HRT. I had low AMH and endo. Since 2024 we had 3 more embryotransfers (1 was PGT-a) tested with the same male… — Anna L.

Dr. Geoffrey Sher answered

We should really discuss this at length. It sounds to me as if you have an implantation dysfunction. Please read the article below and if interested in having an online consultation with me, contact my assistant, Patti Converse (concierge@sherivf.com) and set up an online consultation with me to…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

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