– Geoffrey Sher, MD
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Early Pregnancy & hCG
My last periods was at march 27th and yesterday i had a beta hcg test and it shows 859miu/ml. Am i pregnent? — Hana F.
Dr. Geoffrey Sher answered
Repeat then hCG test in 2 days. It needs to double for confirmation. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A…
i have been a fan of sher for awhile and enjoyed all the postings and article and informative blogs. i noticed that this has stopped over the last several months. i have been looking for informative posts since i am… — Cher R.
Dr. Geoffrey Sher answered
I confess!, I have not been as active with posting blogs in recent months. However, I did pen 2 new ones on our website in the last month or so. I will try to do better going forward. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to…
Egg Health & Ovarian Reserve
Hi there, I've had 1 MMC and 2 Complete Molar Pregnancies in 2022. I recently had an egg retrieval where they got 22 eggs, 20 eggs were mature and only 7 fertilized via ICSI. I am now waiting to see… — Suman B.
Dr. Geoffrey Sher answered
No! It is not indicative that you cannot conceive with own eggs. A hydatidiform molar pregnancy happens when tissue that normally forms the placenta instead becomes a growth, that triggers symptoms of pregnancy. A hydatidiform mole is a benign tumor of the root system (trophoblast) of the embryo…
Ovarian Stimulation & OHSS
Hi Dr. Sher, I am so upset with myself. Tonight will be my sixth day of taking menopur 75 IUs (along with rekovelle). I was not aspirating it correctly into the syringe and as such, a few times, some of… — Kristin C.
Dr. Geoffrey Sher answered
Don't be too hard on yourself. These things happen. Besides it will likely in no way prejudice your cycle. Good luck and G-d bless! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD).......…
Egg Health & Ovarian Reserve
Dear Dr, what could possible be the cause of having empty follicle on egg retrieval day for ivf. I took the trigger 34hrs before the retrieval and I’m 34yra — Faith A.
Dr. Geoffrey Sher answered
Frequently, when following vigorous and often repeated flushing of follicles at egg retrieval they fail to yield eggs, it is ascribed to “Empty Follicle Syndrome.” This is a gross misnomer, because all follicles contain eggs. So why were no eggs retrieved from the follicles? Most likely it was…
Clinic & Practice
Do you have the option of doing monitoring out of state or city if you don't live in NY? — Patty M.
Dr. Geoffrey Sher answered
We do accommodate this, but my preference would be to do this all-important part of treatment with us in NY. Geoff Sher Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss…
Embryos & Genetic Testing
Hello Dr. Sher, I just heard your interview about recurrent implantation failure on Dr. Aimee’s podcast. I am 33 years old, no known fertility issues, my husband and I are doing IVF with PGT-A/M for genetic purposes. I have had… — Alayna D.
Dr. Geoffrey Sher answered
Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss (RPL), and in women with underlying endo-uterine surface lesions, thickness of the uterine lining (endometrium) and /or immunologic factors. IVF success rates…
Uterine & Endometrial Health
I understand you offer PRP therapy? I am 44 with DOR and several failed IVF cycles. Would you recommend? If so, what is involved? — Patty M.
Dr. Geoffrey Sher answered
WE do offer PRP for those who wish to indulge...,And, there are differences of opinion, but I am not a proponent of PRP. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for…
Early Pregnancy & hCG
My bita HCG results is 792.35 and flag is h and ref. range is 0-5.0 mean I'm pregnant or not?? — Puja B.
Dr. Geoffrey Sher answered
Strongly suggests pregnancy, I know of no medical announcement associated with the degree of emotional anticipation and anguish as that associated with a pending diagnosis/confirmation of pregnancy following infertility treatment. In fact, hardly a day goes by where I am not confronted by a patient anxiously seeking interpretation…
Embryos & Genetic Testing
I would like to find out ways in which I can maximize my ability to have a successful FET. I have had four (4) transfers with untested embryos and none of them implanted. I recently did a retrieval and I… — Tracey-Ann H.
Dr. Geoffrey Sher answered
Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss (RPL), and in women with underlying endo-uterine surface lesions, thickness of the uterine lining (endometrium) and /or immunologic factors. IVF success rates…
IVF Failure & Pregnancy Loss
I am 36 y/o and have five pregnancies, with one living child delivered at 36 wks (spontaneous birth). Hyperthyroidism caused by Graves disease is my only chronic medical condition. My husband and I have both been genetically tested. The RE… — Sade S.
Dr. Geoffrey Sher answered
Currently, with few exceptions, practitioners of assisted reproduction tend to attribute “unexplained and/or repeated” IVF failure(s), almost exclusively to poor embryo quality, advocating adjusted protocols for ovarian stimulation and/or gamete and embryo preparation as a potential remedy. The idea, having failed IVF, that all it takes to ultimately…
Embryos & Genetic Testing
Hi doctor , I have pgt a tested embryos which failed in 3 FET. My frozen embryos are over now and I’m diagnosed with ssa ro positive and all other tests negative. I was given intralipids last two times and… — Rakshitha R.
Dr. Geoffrey Sher answered
Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss (RPL), and in women with underlying endo-uterine surface lesions, thickness of the uterine lining (endometrium) and /or immunologic factors. IVF success rates…
Uterine & Endometrial Health
I lost my Ivf twins at 19 weeks due to incompetent cervix. My OB refused to give me a d&c until 3 months postpartum because she didn’t believe I had retained products even though I told her my body was… — Michelle K.
Dr. Geoffrey Sher answered
Clearly the retained products of conception (for such a long time period), caused endometritis that compromised the basal endometrium, rendering it unable to respond optimally to estrogen. In my opinion, the D&C was probably delayed for too long. This may or may not be reversible (see below). It…
Embryos & Genetic Testing
We have been dealing with fertility issues for 18 months. Last year, I had three early miscarriages (all at less than 8 weeks). These miscarriages occurred back-to-back-to-back within a 7 month period. We were referred to an REI. Since then,… — Morgan H.
Dr. Geoffrey Sher answered
Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss (RPL), and in women with underlying endo-uterine surface lesions, thickness of the uterine lining (endometrium) and /or immunologic factors. IVF success rates…
Immunology & Implantation
Is it true that some women with hashimotos will have no issues getting and staying pregnant? While others will suffer from recurrent loss? What causes this discrepancy? — M J.
Dr. Geoffrey Sher answered
Between 2% and 5% of women of the childbearing age have reduced thyroid hormone activity (hypothyroidism). Women with hypothyroidism often manifest with reproductive failure i.e. infertility, unexplained (often repeated) IVF failure, or recurrent pregnancy loss (RPL). The condition is 5-10 times more common in women than in men.…
