– Geoffrey Sher, MD
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Third-Party Reproduction
Clínicas para un asesoramiento — Luisa L.
Dr. Geoffrey Sher answered
Please redraft your question in English! Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ; http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf Recurrent Pregnancy Loss and…
Third-Party Reproduction
Dear Dr. T, When is one directed towards the surrogacy option? Thank you. — Y M.
Dr. Geoffrey Sher answered
IVF surrogacy involves the transfer of one or more embryos into the uterus of a surrogate, who provides a host womb and carries the baby to term, but does not contribute genetically to the baby. Typically, the intended mother provides the eggs and her partner (the intended father)…
IVF Failure & Pregnancy Loss
Hi, I just had my 3rd failed FET. 1st one was negative, second one we got pregnant but resulted in a chemical (pregnant for 5 days, we used Letrozole), 3rd one completly negative. I am very confused and loosing hope.… — Erin C.
Dr. Geoffrey Sher answered
__ If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let's explore some common reasons for IVF failure in simpler…
Embryos & Genetic Testing
Hi Dr Sher, My husband and I are using donated embryos from a clinic program after 8 rounds of failed IVF due to low AMH 0.19 & diminished ovarian reserve. I have endometriomas in my ovaries and am now 44… — Naz C.
Dr. Geoffrey Sher answered
It is important to understand that endometriosis can be associated with an autoimmune, immunologic implantation dysfunction in about 30% of cases (regardless of its severity). This should, in my opinion, be thoroughly evaluated before transferring any more of these embryos! In the world of assisted reproduction, when IVF…
Third-Party Reproduction
Hello. Me and my husband are researching for family planning and when googling your website really stood out with sound and solid information. I have a question which I havent bern able to find a conducive answer for. Im 41… — Azadeh B.
Dr. Geoffrey Sher answered
It is the age of the egg provider that is more important (see below) Geoff Sher Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these…
Third-Party Reproduction
I had my first egg donor transfer at 43 years old and it was successful. Had a c-section with no complications. Now I am 47 years old and wanted to try once more. This time I have had 4 transfer… — Alicia C.
Dr. Geoffrey Sher answered
It is possible that with established menopause, the chronically low estradiol has suppressed endometrial estrogen receptors, rendering the lining refractory to short-term estrogen stimulation. In my opinion you s might try a few months of cyclical estrogen/progesterone therapy to try and prime the endometrium (reawaken estrogen receptor response).…
Immunology & Implantation
Hi Dr. Sher, I’m writing you at a complete loss and low point in my treatment. I am 34. My husband is 41. We started to try to conceive when I was age 31 and within 3 months, I became… — Alyssa J.
Dr. Geoffrey Sher answered
There is very likely to be an implantation dysfunction. We should talk. I suggest you call my assistant, Patti Converse (702-533-02691 and set up an online consultation with me. Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. In the pursuit of optimizing outcome…
Immunology & Implantation
Hello Dr Sher, I have elevated NK cells and even after completing a full immune protocol (ivig, intrallipids) my NK cells went from 15.6 down to 14.9. My husband and I have a full DQ alpha match and no matter… — Melissa K.
Dr. Geoffrey Sher answered
In my opinion...you would face the same issues . It is not recommended! This is about your genotype and that of the sperm that fertilized the egg. It is not about egg and sperm. Read the additional information below! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links…
Third-Party Reproduction
Hi We are based in the UK and want to know your live birth success rates for patients using egg donor, with a diagnosis of Adenomyosis and Endometriosis. I am also age 47 yrs and understand that there are risks… — Fiona F.
Dr. Geoffrey Sher answered
Adenomyosis-Related Infertility: A Therapeutic Challenge! Geoffrey Sher MD Adenomyosis is a condition where endometrial glands develop outside the uterine lining (endometrium), within the muscular wall of the uterus (myometrium). Definitive diagnosis of adenomyosis is difficult to make. The condition should be suspected when a premenopausal woman (usually>25 years…
Embryos & Genetic Testing
Hi Dr. Sher, I have a child conceived naturally at 39 and then two early miscarriages also natural conception (first loss at 6 weeks and second loss at 7 weeks prior to heartbeat being detected) at age 42 and age… — Eliana B.
Dr. Geoffrey Sher answered
This is highly likely to at least in part, be due to a secondary implantation dysfunction (see below). While not definitive, I suspect an immunologic implantation dysfunction (IID). The fact that you have had a child already means that it if an IID exists, it is possibly alloimmune…
Immunology & Implantation
I have had 5 DE failed cycles. I’m Kir-Aa, I have Hashimotos, and I’ve been on Lovenox, Prednisone and Aspirin for the last 3 rounds and still failed despite high quality embryos. The donor was HLA. Now we can start… — Sophie W.
Dr. Geoffrey Sher answered
WE really should talk! To me it seams that there is an underlying implantation dysfunction that is likely immunologic in origin. If I am correct then respectfully, in my opinion, the treatment to address the immunologic implantation dysfunction (IID) was not optimal/adequate.I invite you to contact my assistant,…
Egg Health & Ovarian Reserve
I am 32, have PCO. I have experienced EFS in all egg collections, medicated and unmedicated. Recently, I found out I have ZP1 homozygous mutation (autosomal recessive) which means maturation oocyte defect. Is there a way to find eggs or… — Andria E.
Dr. Geoffrey Sher answered
There is certainly room for differing opinions her, But I would not go straight to egg donation. There are so many factors that impact egg quality in women with PCOS, but most of them are amenable to treatment using an individualized protocol for ovarian stimulation. Polycystic ovary syndrome…
Third-Party Reproduction
Using another doner — Mary L.
Dr. Geoffrey Sher answered
Please clarify your question/issue!
Embryos & Genetic Testing
I have done an I VF and I am right now in the two week wait anxiety . I have tried 4 times previously and have a failure . The doctor this time did surgical scratching for the uterus ,… — Monica E.
Dr. Geoffrey Sher answered
I suggest you await the outcome and if you do not conceive, that you contact my assistant Patti Converse (702-533-2691) and set up a consultation online, with me. Good luck! Geoff Sher
Third-Party Reproduction
Hi at what age can a daughter donate eggs to mothers based on your website I see you did this once thanks — Jan R.
Dr. Geoffrey Sher answered
I have done this > once. The daughter needs to be >18y and preferably over 21y. Geoff Sher
