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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Answers from our doctors

Search 1,006 questions patients have already asked, or narrow them by topic.

  1. Immunology & Implantation

    Secondary Recurrent Pregnancy Loss and possible IID

    Hi Dr Sher, I am 40 years old and have suffered with a number of early pregnancy losses in the past year, all conceived naturally. I have a 3 year old son who was conceived easily with no issues during… — Bronagh M.

    Dr. Geoffrey Sher answered

    When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…

  2. Infertility Basics

    RPL, Secondary Infertility

    Hello Dr. Sher, I am experiencing my 4th biochemical pregnancy in less than 2 years. I am 45 years old with 8 previous live births. My youngest son turned 2 years old in January. I recently acquired Day 3 labs… — Faith R.

    Dr. Geoffrey Sher answered

    I am attaching an article I wrote on RPL but I would like to preface this by saying that at 45y of age, and especially with concomitant DOR, the large majority of your eggs will be aneuploid and resulting embryos too. Such embryos, if they implant will be…

  3. IVF Failure & Pregnancy Loss

    Yulissa

    Aserca de mi tratamiento — Yulissa A.

    Dr. Geoffrey Sher answered

    Please re-post in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility…

  4. Embryos & Genetic Testing

    Recurrent biochemical & Ectopic

    Hi Dr Sher, Could you please try and answer what could be causing my issue and possible solution. I am 38 (husband 40) and we are married for 13 years; trying for a child since 10 years. I never had… — Indira V.

    Dr. Geoffrey Sher answered

    When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…

  5. IVF Failure & Pregnancy Loss

    I need help with ivf

    Hi . I try ivf I don’t get pregnant :( I want baby but I can’t pay a lot money I don’t have :( I need help plz — Ikhlas D.

    Dr. Geoffrey Sher answered

    If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let's explore some common reasons for IVF failure in simpler terms.…

  6. IVF Failure & Pregnancy Loss

    Female miscarriages

    Pleaze call [phone number removed] — Charlotte L.

    Dr. Geoffrey Sher answered

    I suggest you call my assistant, Patti Converse at 702-533-2691 and set up an online consultation with me to discuss. Geoff Sher When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births,…

  7. Embryos & Genetic Testing

    IVF Failure/ embryo issue

    Hello Dr. Sher, I just watched a video of your interview with Dr. Aimee regarding RIF. I am age 36 with 5 failed to implant IUI's and 2 IVF retrievals with donor sperm. Prior to now I never tried to… — Michelle D.

    Dr. Geoffrey Sher answered

    ADDRESSING DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols…

  8. Immunology & Implantation

    Recurrent miscarriage

    Dr sher In the past 2 years I have had 2 mmc one at 6 weeks and one at 9 weeks. The products were tested of the 9 week one it was genetically normal. After that I have had 3… — Tara B.

    Dr. Geoffrey Sher answered

    Having done the tests you describe has no real merit if they were not done at one of about 4 Reproductive Immunology Laboratories in Th US that can do these tests with optimal specificity and sensitivity. We need to talk! I invite you to contact my assistant, Patti…

  9. IVF Failure & Pregnancy Loss

    Infertility

    Can letrozol and omega3 take together during period — Bamikole O.

    Dr. Geoffrey Sher answered

    Yes! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ;…

  10. Embryos & Genetic Testing

    Recurrent Implantation Failure

    Hello Dr. Sher at my current clinic I have gone through 4 transfers with PGT-A normal embryos. My first transfer resulted in a chemical pregnancy, but the following transfers did not implant at all. The tests I have done are… — Ashley P.

    Dr. Geoffrey Sher answered

    In my opinion this is almost certainly an implantation dysfunction. Bear in mind that in 30% of cases, endometriosis is associated with an immunologic implantation dysfunction. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or…

  11. IVF Failure & Pregnancy Loss

    Next Steps

    aI am a 36 y.o. female with PCOS. I have had 2 miscarriages at 6 weeks (1 from an IVF transfer recently and 1 from letrozole round several years ago) , and 2 failed IVF transfers that failed to implant.… — Christy L.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  12. IVF Failure & Pregnancy Loss

    Recurrent Implantation Failure

    Hello! I am a 24 y.o. female, Gravida 0, AMH 0.2-0.8, four failed IUI’s, and now 4 failed transfers with 5 embryos never implanting. I’ve done two ERA’s (both postreceptive at 96 and 72 hours) but we’ve ignored these results… — Delaney D.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  13. IVF Failure & Pregnancy Loss

    Ivf

    Dr am 44 had a miscarriage in October naturally without ivf thinking of starting ivf last period was January 21 until date no flow and am not pregnant your advice pls and thxs — Vera E.

    Dr. Geoffrey Sher answered

    _ Age should never be a barrier to hope and fulfillment when it comes to IVF. Many women in their early to mid-40s are successfully having IVF babies using their own eggs, especially if they have a good number of eggs left in their ovaries. However, for women…

  14. Hormones & Ovulation

    Failed ivf cycle

    Hello doctor; i am 32 yo female, amh 1.59 ng/ml. Partner 32 years old with varicocele, 0 morphology and very low count. (Impossible to check for dna fragmentation) I am Insulin resistant, on metformin 750 for 5 months now with… — Nino K.

    Dr. Geoffrey Sher answered

    There clearly is both male factor infertility and diminished ovarian reserve (DOR). Both issues need to be thoroughly evaluated and addressed. The cause of the male factor will need further testing and the DOR requires a very individualized approach to ovarian stimulation...(see below). I strongly suggest that you…

  15. Embryos & Genetic Testing

    Multiple failures after live birth from IVF

    My first FET in 2020 was successful and resulted in the birth of my son. Since 2022, I have had four more FETs: the first one failed to implant and the next three implanted but miscarried between 5-6 weeks. The… — Kelsey H.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

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