– Geoffrey Sher, MD
Fill in the following information and we’ll get back to you.
Search 1,009 questions patients have already asked, or narrow them by topic.
Page 38 of 68
Embryos & Genetic Testing
Hi Dr Sher, apologies to bother you again, your insights are so helpful and I'm worried this IVF round isn't going to work! It's a Euploid embryo being transferred that I don't want to wast. We're doing a modified natural… — Cassidy O.
Dr. Geoffrey Sher answered
No! It sounds as if the timing will still be OK! Good luck! Geoff Sher
Embryos & Genetic Testing
I went in for a scan today in anticipation of doing a modified natural cycle, it's day 10 - LH levels are rising -I've not reached ovulation yet, LH normally surges on day 14 for me. The lining was trilaminar… — Cassidy O.
Dr. Geoffrey Sher answered
Candidly, I am not a fan of modified natural cycle FET's. However, the time to trigger is just before the onset of the natural LH surge.; This is determined by the size (20+mm) of the dominaqnt follicle and bloopd E2. (150pg/ml+ or 300+ if there are >2 dominant…
Ovarian Stimulation & OHSS
I am 42, 2.15 AMH, did the first cycle with Decapeptyl only and got all empty follicles. Then did three more cycles with dual trigger and got no euploids. Should I try an Ovidrel only trigger? 500 or 250? (I… — Anne C.
Dr. Geoffrey Sher answered
Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely to happen when multiple attempts are needed to retrieve an egg from a follicle, indicating the egg may have chromosomal abnormalities. The…
Clinic & Practice
To whom it may be concerned, I am Dr. Amy Huang's patient. After more than one year of getting pregnancy naturally, we decided to move forward with other options. I got referral from Dr. Huang and would like to make… — Yuyan Q.
Dr. Geoffrey Sher answered
Thanks for contacting me. Please call 702-533-2691 and ask my assistant, Patti Converse, to set you up with an online consultation with me. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In…
IVF Failure & Pregnancy Loss
Hello... My name is Claire...I've had 3 pregnancy losses ..one was at 6weeks and the rest were chemical pregnancies they exited even before I noticed I was pregnant..my gyna did thyroid.. diabetes and immune disorder test with my blood and… — Claire L.
Dr. Geoffrey Sher answered
When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Embryos & Genetic Testing
Hi, I came across your podcast about implantation issues. I went thru infertility issues for 4 years (Ivf wasn’t covered) 19iuis- I had a miscarriage in the 2nd trimester- 3 chemical pregnancies and 2 miscarriages ending before 9 weeks we… — Lauren B.
Dr. Geoffrey Sher answered
Clearly you have recurrent pregnancy loss...likely due to an implantation dysfunction (anatomical or immunologic.However, I would need much more information to be able to comment authoritatively. When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not…
Egg Health & Ovarian Reserve
Dear Dr. Sher, 42 year old here desperately wanting to be mother for the first time! 6 year unknown infertility, 99 lbs, 5'6'', eat healthy, taking COQ10 and prenatal, very healthy and no disease illnesses in the past. My AMH… — Anne C.
Dr. Geoffrey Sher answered
Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…
Egg Health & Ovarian Reserve
Hi, quick background info- 37 years old, husband is 48 years old. I have stage 4 endometriosis with bilateral endometriomas about 4-5 cm on both ovaries. AMH of 3.8, FSH 5.5, Estradiol 45. Sperm analysis is above normal. I just… — Marie F.
Dr. Geoffrey Sher answered
When women with infertility due to endometriosis seek treatment, they are all too often advised to first try ovarian stimulation (ovulation Induction) with intrauterine insemination (IUI) ………as if to say that this would be just as likely to result in a baby as would in vitro fertilization (IVF).…
Early Pregnancy & hCG
hello, i am very concerned about my heavy bleeding despite being pregnant. my hcg numbers went from 624 to 737 in 5 days. is this normal — Ruth J.
Dr. Geoffrey Sher answered
Sadly, this suggests that the pregnancy is non-viable. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ; http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf Recurrent Pregnancy…
Immunology & Implantation
Dear Dr Sher, I am a 33 year old European woman currently TTC. I had my first conception success in 2022, in about 9 months period time and had a pregnancy loss before 8 weeks. Since then I was not… — Elia F.
Dr. Geoffrey Sher answered
The complete match is only a problem if in addition you have activated natural killer cells. ...see below. Geoff Shedr In the world of assisted reproduction, when IVF fails repeatedly or without explanation, it's often assumed that poor embryo quality is the main culprit. However, this view oversimplifies…
Hormones & Ovulation
Hello my name is James my wife and I been trying to conceive for the last year . The clinic we went said my wife would have to lose 60lbs before treatment. What is the Bmi requirements at your clinic… — James C.
Dr. Geoffrey Sher answered
Obviously women that are much overweight will have more difficulty in pregnancy. However we have no absolute BMI cut=-off requirements presently! Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization…
Ovarian Stimulation & OHSS
I had follicle measuring 15mm with estrogen 155 and 5 days later estrogen dropped to 106. This is from natural cycle using no stimulation. The clinic wanted to aspirate and fertilize then decided not to due drop in estrogen and… — Jumna P.
Dr. Geoffrey Sher answered
Your RE made the right decision. That follicle would not have propagated a good egg! Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher…
Embryos & Genetic Testing
Hello Dr. Sher, After having two miscarriages (1 natural and 1 IUI), I found out that I have a robertsonian balanced translocation (13:14). My RE said that my best bet would be to do IVF with PGT-SR testing. I did… — Caitlin D.
Dr. Geoffrey Sher answered
The fact that the embryo transferred was euploid does not guarantee that it is was normal. There are genetic and metabolic factors that also can play a role. As for the low yield of "competent embryos, that likely has to do with the protocol used for ovarian stimulation.…
Immunology & Implantation
Dear Dr Sher, I have a history of 5 natural pregnancies complicated by pre-eclampsia, 2 previous csection births. After my last birth via csection, i have had 3 first trimester miscarriages. I'm now undergoing ivf with donor eggs due to… — Lisa W.
Dr. Geoffrey Sher answered
It is indeed possible that you have acquired an immunologic implantation dysfunction. In the world of assisted reproduction, when IVF fails repeatedly or without explanation, it's often assumed that poor embryo quality is the main culprit. However, this view oversimplifies the situation. The process of embryo implantation, which…
Embryos & Genetic Testing
Could this be a early sing of miscarriage? HGC levels have growth 35% form 3 days ago. — Daniela M.
Dr. Geoffrey Sher answered
I am afraid that bhis does not look promising. I hope I am proven wrong but I think you are likely t5o lose this pregnancy. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello…
