– Geoffrey Sher, MD
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Age & Fertility
I am 42 old woman, planning for IVF in next few months. What supplements, dosage and duration would you recommend for me? Thank you — Pema L.
Dr. Geoffrey Sher answered
The Role of Nutritional Supplements in Preparing for IVF Geoffrey Sher MD It is important to nurture and take care of yourself mentally and physically when preparing and going through your IVF journey. This starts with trying to have a positive attitude about what you are about to…
Age & Fertility
Hi Dr Sher, I’m 43 yrs old & had a baby with IVF at 41 using the mini stim protocol (fresh) & hoping to try again for a 2nd. We’ve had 3 failed cycles since (using way higher doses). The… — Rosie S.
Dr. Geoffrey Sher answered
Frozen transfer of PGS-normal blastocyst is preferable in my opinion. With regard toi stimulation, consider the following: Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify…
Age & Fertility
I am 42 years old and had 1 failed IVF. I had 15 follicles, 11 retrieved, 6 became embryos but all 6 had chromosome abnormalities.. Is it worth doing IVF again — Tasneem K.
Dr. Geoffrey Sher answered
Yes, provided that an optimal protocol is used for ovarian stimulation. Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in…
Age & Fertility
I am 43 years old and had a failed IVF cycle. My AMF is .615. I was on Luperon, menopur and follistim. I had 5 mature eggs and 4 fertilized. Two made it to day 5 which one was a… — Allison L.
Dr. Geoffrey Sher answered
Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…
Age & Fertility
Hi Dr. Sher, I am in the process of freezing embryos. I have both endometriosis and severe fibroids. I’ve had one abdominal myomectomy and several laparoscopies to remove endo and fibroids over the years and as we are planning for… — Rebecca M.
Dr. Geoffrey Sher answered
I would really need much more information to provide an authoritative opinion. Feel free to call 702-533-2691 to set up an online consultation to discuss in depth. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY…
Age & Fertility
Hello Dr Sher I have diminished ovarian reserve. My AMH 2 yrs ago was 0.36. Its likely even lower now :( I have been a poor responder to high dose IVF with gonal-f (450 units) and menopur 150 units. Prior… — Yvette R.
Dr. Geoffrey Sher answered
It is primarily the egg (rather than the sperm) that determines the chromosomal integrity (karyotype) of the embryo, the most important determinant of egg/embryo competency”. A “competent” egg is therefore one that has a normal karyotype and has the best potential to propagate a “competent” embryo. In turn,…
Age & Fertility
Hello Dr, Sher, from one South African to another :) I am living in Portugal now, and am trying to fall pregnant. I have been diagnosed with diffuse adenomyosis (mild) which is at the top of my uterus. Mainly on… — Lisa-Marie E.
Dr. Geoffrey Sher answered
Respectfully, I do not agree. Both age and diminishing ovarian reserve, make this a poor choice. I would move to IVF ASAP . Frankly , unless your adenomyosis is associated with a "thin uterine lining at mid-cycle, I would not be over concerned about this aspect.I am including…
Age & Fertility
Hello Dr. I am turning 40 this year and have pcos. Can you explain why my AMH is still very high? 12 years ago it was 10 ng/ml, now it’s 6.85. I also used to have 15 follicles on each… — Amanda B.
Dr. Geoffrey Sher answered
It ism true thatvwo9men with PCOS have an increased risk of developing breast and ovarian cancer. However, this is by no means a great risk. You need to have regular check-up evaluations at least yearly, but I would not become paranoid about this. In the vast majority of…
Age & Fertility
What is in your opinion the best IVF protocol for a 46 year old with FSH 19 and AMH 0.51, poor responder, 4 canceled IVF cycles turned into IUI because of dominant ovarian follicle and only 1 egg retrieval of… — Nari J.
Dr. Geoffrey Sher answered
Very respectfully, the chance of IVF success at 46y with these parameters is negligible. Of course it would be your right to try, but in my opinion, only IVF with egg donation would offer success! Geoffrey Sher The importance of the IVF stimulation protocol on egg/embryo quality cannot…
Age & Fertility
Hi, for women age 41+ with low ovarian reserve what are options to conceive successfully using own eggs? I've been discouraged with clinic's pushing donor eggs and I am looking for a specialist that can help someone like me. Any… — Newbie F.
Dr. Geoffrey Sher answered
It is primarily the egg (rather than the sperm) that determines the chromosomal integrity (karyotype) of the embryo, the most important determinant of egg/embryo competency”. A “competent” egg is therefore one that has a normal karyotype and has the best potential to propagate a “competent” embryo. In turn,…
Age & Fertility
Hello Dr, I have pcos and I am 40 years old. I have an 8 year old and over the years, I’ve been through 7 rounds of timed intercourse with ovidrel with no success. My doctor is recommending a round… — Marcella J.
Dr. Geoffrey Sher answered
Ever since January 1993 when a study was reported by researchers at Stanford University suggesting that the use of fertility agents increased the risk of ovarian cancer, there has been tremendous concern and anxiety among women who use fertility drugs. At first the findings seemed well founded because…
Age & Fertility
Dear Dr. Sher, I’d like to know if you have an age limit for assisting a post-menopausal woman to get pregnant with IVF? 50, 55, 60, 65 .. ? Thank you, ~Beth — Beth R.
Dr. Geoffrey Sher answered
Our cut off using own eggs is 47y. In my opinion doing IVF with own eggs over 43y is not wise. However, there is no definitive cut-off when donor eggs are used. I believe this very much depends on the health of the individual patient. Geoff Sher ADDITIONAL…
Age & Fertility
Hello Dr Sherr, I’m 42 years old and I just had my first baby through IVF delivered through C section. How long would you recommend to wait before trying for the second baby. In my case my advanced age might… — Natalia B.
Dr. Geoffrey Sher answered
CONGRATULATIONS!! I would suggest waiting until you have stopped breast feeding and have since experienced at least 2 regular menstrual cycles. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading…
Age & Fertility
Hello Hello, I am not sure my last email went through. we were successful with Elin Fifer being born on 8/28/2013. I am from Colorado and saw you 3 times. Elin is extremely smart and tested a high IQ. she… — Elizabeth A.
Dr. Geoffrey Sher answered
I personally do not see this as an absolute contraindication. The dosage would be the same! I do however suggest you discuss this with a Hematologist. Geoff Sher
Age & Fertility
Dear Dr. Sher, thank you very much for all the things you do for our community of fertility warriors. I have heard that gonadotrophins stimulation in older women with low ovarian reserve should only be done with FSH and no… — Shira M.
Dr. Geoffrey Sher answered
It is primarily the egg (rather than the sperm) that determines the chromosomal integrity (karyotype) of the embryo, the most important determinant of egg/embryo competency”. A “competent” egg is therefore one that has a normal karyotype and has the best potential to propagate a “competent” embryo. In turn,…
