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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Search 1,006 questions patients have already asked, or narrow them by topic.

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  1. IVF Failure & Pregnancy Loss

    chemical pregnancy

    I had endometriosis excision surgery two months ago and was diagnosed with endometriosis stage 4, I got pregnant on the second full cycle after it, but it ended in a chemical pregnancy which is my second chemical pregnancy overall. I… — Caroline J.

    Dr. Geoffrey Sher answered

    Here is an article I wrote on endometriosis and infertility. We should talk. Please email Patti , my assistant at concierge@sherivf.com and she can arrange for us to have an online consultation to discuss. Geoff Sher Endometriosis and Infertility The Hidden Disease: What Every Woman Trying to Conceive…

  2. IVF Failure & Pregnancy Loss

    reoccurring miscarriage

    Progesterone levels aren’t high enough to support my pregnancies. What do i do? — Aslinn N.

    Dr. Geoffrey Sher answered

    We would need to talk. However there is much more to RPL than low progesterone levels. The latter is often the result of a failing trophoblast (embryo root system)...not the cause of it. If you would like to talk to me about the specifics of your case, please…

  3. IVF Failure & Pregnancy Loss

    RIF

    I’ve had multiple frozen embryo transfers with no implantation - 4. I’d like an online consultation with Dr. Sher to review my history and get a personalized plan. — Monica J.

    Dr. Geoffrey Sher answered

    I invite you to contact my Office Manager, Patti Converse (702-533-2691 and set up an online consultation with me. Geoff Sher IMPLANTATION DYSFUNCTION Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are…

  4. Embryos & Genetic Testing

    Recurrent Natural Pregnancy Loss followed by Recurrent Implantation Failure

    I (33 years old) have a small piece of "benign" genetic material (#15) mosaically which may be contributing to recurrent natural pregnancy loss (4 losses, 2 were between 10-16 weeks with confirmed T18 and T21). Genetic Counselors could not confirm… — Sam L.

    Dr. Geoffrey Sher answered

    WE really need to talk. I invite you to contact my Office Manager, Patti Converse (702-533-2691 and set up an online consultation with me. UNDERSTANDING RECURRENT PREGNANCY LOSS ( RPL): CAUSES AND SOLUTIONS. When it comes to reproduction, humans face challenges compared to other mammals. A significant number…

  5. Embryos & Genetic Testing

    Recurrent Pregnancy Loss

    I have a history of autoimmune and clotting issues possibly contributing to recurrent pregnancy loss (4 losses, 2 from IVF) and currently have 6 frozen PGT-A tested embryos at Shady Grove Fertility (4 euploid, 2 mosaic). I no longer have… — Katie B.

    Dr. Geoffrey Sher answered

    UNDERSTANDING RECURRENT PREGNANCY LOSS ( RPL): CAUSES AND SOLUTIONS. When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending…

  6. Immunology & Implantation

    Reproductive Immunology

    Hello, I have had two, late, second trimester losses, back to back. Both of these losses have happened since I was diagnosed with a rare autoimmune, eosinophillic esophagitis. What is your familiarity with reproductive immunology and how likely is there… — Kathryn C.

    Dr. Geoffrey Sher answered

    In the world of assisted reproduction, when IVF fails repeatedly or without explanation, it's often assumed that poor embryo quality is the main culprit. However, this view oversimplifies the situation. The process of embryo implantation, which begins about six or seven days after fertilization, involves a complex interaction…

  7. Embryos & Genetic Testing

    Recurrent Failed implantation

    H! Dr. Sher , I am honored to have a chance to ask you some questions about IVF . My husband and I just had a failed embryo transfer which was our 4th transfer with a euploid embryo and all… — Maria P.

    Dr. Geoffrey Sher answered

    Thank you for your communication. Below please find information that I feel confident will help explain the possible reasons for implantation dysfunction. Thereupon, if you would like to have a consultation with me to discuss your circumstances and potential remedies, please call or text my assistant, Patti Converse…

  8. Embryos & Genetic Testing

    Repeat failed implantations

    I have experienced one miscarriage and four failed implantations with untested embryos. In my recent IVF cycle, I obtained one PGT-A–tested 5AB euploid embryo. I also underwent a hysteroscopy with a uterine biopsy to investigate the failed implantations, and all… — Fab W.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  9. Hormones & Ovulation

    FET

    Hello! I had a recent FET just a few days ago. On the day oftransfer, my progesterone was 37 and estradiol was 1700. This estradiol level is considerably higher than it was for my last successful FET. So I am… — Eugenia T.

    Dr. Geoffrey Sher answered

    The E2 level, ideally, should be 500-100pg/ml on the day progesterone treatment starts. Endometrial thickness is measured also on the day progesterone starts. It needs to be >8mm with a trilaminar ultrsound appearance, The thickness on the day of transfer is not significant. See the article below, on…

  10. IVF Failure & Pregnancy Loss

    Implantation failure regarding

    Hello Doctor, I have a query regarding repeated implantation failure. I have low amh and my spouse has severe Oligoasthenoteratozoospermia(only 2 sperm found even under the highest resolution). So we opted for donor eggs and donor sperms. But overall I… — Shilpa M.

    Dr. Geoffrey Sher answered

    IMPLANTATION DYSFUNCTION Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors.…

  11. Immunology & Implantation

    Implantation Failure – BCL6, immature nk cells & APS

    Hello Dr, After multiple implantation failure, I was diagnosed with anti-phospholipid syndrom (managed with daily asprin and in case of pregnancy clexane) but also high inflammation marker BCL6 (though no endometriosis) and immature NK cells / low local immune activation… — Kate F.

    Dr. Geoffrey Sher answered

    I have strong suspicion that you have an immunologic implantation dysfunction. IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are…

  12. Early Pregnancy & hCG

    Mold/mycotoxin antibodies

    Hi! I have a history of recurrent miscarriage but also have 2 living children. I’ve been exposed to mold in the past so had recent testing done. Many of my IgE antibodies to mold/mycotoxins were high, suggesting a current mold… — Sarah R.

    Dr. Geoffrey Sher answered

    I honestly doubt that this is what has caused your miscarriages,. But discuss it with your primarybcare OB/GYN. Geoff Sher

  13. IVF Failure & Pregnancy Loss

    MOLAR PREGNANCY PREVENTION

    MY WIFE HAD 2 CONSECUTIVE COMPLETE MOLAR PREGANANCIES AT AGE 24 AND 25. THEN SHE APPROACHED IVF, AND RETURNED A MALE EMBRYO BASED ON DR. SHER'S ARRICLE IN 2016 AS SOLUTION TO PREVENT A COMPLETE MOLE. MY QUESTION NOW, IS… — Ahmad A.

    Dr. Geoffrey Sher answered

    Not to my knowledge! Sorry! Geoff Sher

  14. IVF Failure & Pregnancy Loss

    Cervix dilated

    At20weeksinmyivfpregnacymycervixdilatedandledtostillbirth.what could be the reason — N R.

    Dr. Geoffrey Sher answered

    This sounds like cervical incompetence . You likely leaked fluids after the membranes ruptured and the fetus was infected. This is something that can be treated through the insertion of a cervical cerclage. Discuss it with your Obstetrician. Geoff Sher

  15. IVF Failure & Pregnancy Loss

    RPL

    I was excited to see the depth of understanding and research regardingRPL.i am having my third miscarriage at6-7weeks. Could I schedule a telehealth consult? — Jane M.

    Dr. Geoffrey Sher answered

    Absolutely you can. Email my assistant, Patti Converse at concierge@sherivf.com with your telephone # and she will call you right back and set this up. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure:…

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