At Sher Fertility Solutions, we understand that each patient is unique. Everything we do is customized to you and your specific needs.
As you may be aware, the Braverman Center has closed and will no longer be offering immunology services.
Dr. Sher, a pioneer in reproductive immunology, was largely instrumental in training Dr. Braverman during his time at Sher Fertility Solutions some years ago.
If you have an infertility problem that you believe might be linked to immunologic implantation dysfunction (IID) and are interested in being evaluated and treated at SFS, please complete the consultation form below.
We’re here to help and we do take insurance.
Once you’ve booked your consultation, you’ll also get immediate access to Dr. Sher’s latest reproductive immunology book “Recurrent Pregnancy Loss and Unexplained IVF Failure: The Immunologic Link”.
All humans have two DQ-alpha genes, one of which is contributed by the
father and the other by the mother. In a small percentage of patients
undergoing IVF, paternal-maternal DQ-alpha gene similarities occur. In
such cases, following repeated exposures to such genetically matching
embryos, this will provoke activation of the decidual immune system.
In most cases, repeated exposure to DQ alpha matching embryos will
over time activate uterine NK cells, resulting in reproductive dy…
Currently there are fewer than a dozen immunology reference
laboratories in the U.S that are capable of analyzing the required
elements with a sufficient degree of sensitivity and specificity as
to be reliable in my opinion. These elements include measuring blood
levels of the eighteen to twenty IgA, IgG and IgM-related APA’s that
are directed against six or seven specific phospholipids, as well as
assessing Natural Killer (NK) cell activity (cytotoxicity) as measured
by their killi…
In 15-20% of women who have infertility or RPL, the cause will be
immunologic implantation dysfunction (IID). Accordingly, all women who
have predisposing factors such as endometriosis, unexplained
infertility/repeated failed IVF, RPL, or have a personal/family
history of primary autoimmune conditions, should be evaluated and
treated appropriately. By doing so, we as phys…
IVF FAILURE AND RECURRENT PREGNANCY LOSS WITH GUEST DR. GEOFFREY SHER
Dr. Geoffrey Sher is an internationally renowned expert in the field
of ART. He trained under the fathers of IVF, Dr. Patrick Steptoe and
Robert Edwards in the UK. He came to the United States in 1982 to
establish the first private non-university-based IVF program, the
fourth IVF clinic in the nation. He then expanded his presence to
include 10 IVF cente…
Central to making a diagnosis of an immunologic implantation
dysfunction (IID) is a need for the appropriate interpretation of
Natural Killer Cell Activity (NKa). In this regard, one of the
commonest and most serious errors, is interpret the blood
concentration of natural killer cells as being relevant. Rather it is
the activity (toxicity) of NK cells that matters as mentioned. This
activity can best be measured using the blood, K-562 target cell test
(the gold standard). and/ o…
In the United States, effective treatment of NK/CTL activation
associated with either alloimmune or autoimmune implantation
dysfunction requires the administration of primarily Intralipid (IL).
Such treatment is much more likely to be successful in the case of`
autoimmune implantation dysfunction where the NK/CTL activation is
present in advance of the uterus being exposed to the embryo. It is
not nearly as effective for the treatment of alloimmune implantatio…
The emphasis we put on innovative, state-of-the-art technology began with our founder, Dr. Geoffrey Sher, one of the pioneers in the field of IVF, who has been influential in the births of more than 17,000 IVF babies. Dr. Sher plays an active role alongside our medical director, Dr. Drew Tortoriello. Together they have over 55 years of clinical and academic experience in the field of Reproductive Medicine.
Together, they were the first to introduce Preimplantation Genetic Testing which vastly increases the chances of IVF success and is now performed worldwide. They also pioneered the testing and treatment of Immunologic Implantation Dysfunction (IID) that frequently leads to “unexplained” infertility, repeated IVF failure, and recurrent miscarriage. We’re able to conduct a variety of other treatments and tests right on site. For example, we offer on-site sperm testing to ensure proper sperm selection techniques are used to create the healthiest possible embryos.
For those women seeking to preserve their fertility, we offer vitrification, a state-of-the-art technology that ensures their eggs will ultimately be thawed successfully.
From the moment you walk into our state-of-the-art New York fertility clinic, you’ll feel the warmth and compassion that will define your experience with us. Drew Tortoriello, MD serves as our Medical Director. He’s an outstanding fertility specialist that you’ll find to be caring, compassionate and personable.
When you receive fertility treatment with us, your doctor will participate with hands-on management of your case throughout your treatment. We’ve gained a reputation of being the place to turn to when all other treatment options have failed, and patients are searching for hope and fresh alternatives.
Sher Fertility Solutions
425 5th Ave.
New York, NY 10016
Dr. Tortoriello (646)792-7476
Dr. Sher (702)533-2691
