If two untested embryos are transferred & one is a normal embryo, the other is abnormal – does the abnormal embryo ‘kill off’ or damage the normal embryo? Thanks 😉
Ask Our Doctors
Supporting Your Journey
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
-
Dear Patients,
I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.– Geoffrey Sher, MD
Fill in the following information and we’ll get back to you.
Embryo Transfer
Name: Rosie S
If two untested embryos are transferred & one is a normal embryo, the other is abnormal – does the abnormal embryo ‘kill off’ or damage the normal embryo? Thanks 😉
Answer:
In my opinion.the concomitant transfer of the abnormal embryo should not prejudice the normal one.
Geoff Sher
_____________________________________________________\
ADDITIONAL INFORMATION:
I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)……. for your reading pleasure:
1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “
https://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf
- “Recurrent Pregnancy Loss and Unexplained IVF Failure: The Immunologic Link
https://drive.google.com/file/d/1iYKz-EkAjMqwMa1ZcufIloRdxnAfDH8L/view
- If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or go to concierge@sherivf.com .
- Also, I have just started a new Podcast https://rumble.com/c/c-3304480. Feel free to take a look-see……… And please spread the word!
Ethanol Sclerotherapy?
Name: Sarah K
Hi, I have what appears to be a 7cm endometrioma on my left ovary. I had surgery to remove an ovarian cyst on the same ovary a year ago and it regrew to the same size within 4 months. An interesting side note is that they tested my last cyst and there were no endometrial cells found, even though the cyst was filled with old blood. They are still calling my new cyst an endometrioma, even though they are not sure it actually is one. My GYN is now suggesting surgery to remove the entire ovary because it regrew so quickly. I would like to avoid surgery if at all possible because I had complications during my last one. Do you offer the ovarian sclerotherapy procedure? If not, do you know who would?
Answer:
I introduced ovarian sclerotherapy using 5% tetracycline hydrochloride (THCL). Unfortunately we cannot access THCL any longer. Therefore, surgery is advised in your case. Personally, it is rarely necessary to remove the entire ovary. In my opinion, the cyst should be isolated and removed leaving most of the ovary intact.
GS
______________________________________________________
ADDITIONAL INFORMATION:
I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)……. for your reading pleasure:
1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “
https://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf
- “Recurrent Pregnancy Loss and Unexplained IVF Failure: The Immunologic Link
https://drive.google.com/file/d/1iYKz-EkAjMqwMa1ZcufIloRdxnAfDH8L/view
- If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or go to concierge@sherivf.com .
- Also, I have just started a new Podcast https://rumble.com/c/c-3304480. Feel free to take a look-see……… And please spread the word!
Fertility and egg rupturing
Name: Tej K
My amh is 20 and now I am into iui treatment. My follicle size is 23mm in right ovary and left ovary pcos . My egg is not rupturing after taking injection also..
Answer:
I would need much more information to respond informatively!
Sorry!
GS
__________________________________________________________________
ADDITIONAL INFORMATION:
I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)……. for your reading pleasure:
1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “
https://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf
- “Recurrent Pregnancy Loss and Unexplained IVF Failure: The Immunologic Link
https://drive.google.com/file/d/1iYKz-EkAjMqwMa1ZcufIloRdxnAfDH8L/view
- If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or go to concierge@sherivf.com .
- Also, I have just started a new Podcast https://rumble.com/c/c-3304480. Feel free to take a look-see……… And please spread the word!
Pregnancy
Name: Rupali S
My HCG level is 1.600.Is it negativd
Answer:
Ye! This is a negative result!
GS
No blastocysts from 2 ivf cycles.
Name: Kamala K
My husband and I are both 29 years, we’ve been trying to conceive since two years and we’ve started visiting a fertility clinic since 11/2022. We’re both healthy, have no other health issues.
Later in March-2023, my AMH fell to 0.79. In April, we decided to move on to IVF due to my falling AMH. April-2023 Ivy cycle 1 AFC: 11, FSH:6, E2:40 We got 10 follicles, 8 mature eggs Day 2, 3: 6
 No blastocysts on day5, day 6 ending we had 3 blastocysts.
The doctor and the embryologist said the growth till day 3 was on track, and slowed to a great extent post that indicating that the embryos might not implant or lead to live birth. We decided to check my husbands DFI and do TESA and PICSI. DFI was 34%.
Ivy cycle 2 FSH: 9.7, E2:22 AFC: 8 SA: all parameters normal, morphology: 1% We got 6 follicles and 6 mature eggs. Day2: 5. Day3: 4. They froze 2 day 3 embryos No blastocysts on day 5 and b/c graded blastocysr on day 6 which doctor said they can’t discard. This cycle, we did TESA + PICSI.
We’re confused to see the same results both these times. What can we do differently the next time and how can we improve our chances?
Answer:
If you’ve undergone in vitro fertilization (IVF) and didn’t achieve a successful pregnancy, you may be wondering why. It’s important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let’s explore some common reasons for IVF failure in simpler terms.
- Age: A woman’s age is a significant factor in IVF success. Generally, women under 35 have a higher chance of getting pregnant through IVF, around 35-40% per embryo transfer. However, this success rate decreases as women get older. For women in their mid-forties, the success rate drops to under 5%. This decline is mainly because the quality of eggs decreases as women age, affecting their ability to develop normally.
Â
- Egg/Embryo Competency: Apart from age, the quality and competency of embryos also affect IVF success. The quality of eggs and embryos is influenced by a woman’s age. However, for older women or those with fewer eggs, the specific IVF protocol used to stimulate the ovaries becomes crucial. A more aggressive approach may be needed to maximize the chances of success. Previously, it was thought that the uterus was better for embryo development than the lab environment. So, early-stage embryos were transferred to the uterus based on their appearance. However, we now know that embryos that have progressed further in development are more likely to be successful. Embryos that don’t reach the blastocyst stage within 5-6 days after fertilization are considered less competent and not suitable for transfer. Additionally, Preimplantation Genetic Sampling / Testing (PGS/T) allows us to check the chromosomes of embryos. This technique helps select the most competent embryos for transfer, especially for older women, those with fewer eggs, repeated IVF failures, and recurrent pregnancy loss.
Â
- Number of Embryos Transferred: Some people believe that transferring more embryos increases the chances of success. While this may have some truth, it’s essential to know that if the problem lies with the ovarian stimulation protocol, transferring more embryos won’t solve it. Also, transferring more embryos doesn’t fix issues related to embryo implantation dysfunction, such as anatomical or immunologic problems. Moreover, multiple embryos can lead to higher-order multiple pregnancies, which pose risks. To minimize these risks, it’s generally recommended to transfer a maximum of two embryos, or even just one, especially when using eggs from young women.
- Implantation Dysfunction (ID): Implantation dysfunction is often overlooked as a cause of unexplained IVF failure, especially in young women with normal ovarian reserve and fertile partners. Failure to identify and address these issues can result in repeated IVF failures. If transferring competent embryos repeatedly fails to result in a viable pregnancy, implantation dysfunction should be considered. The most common causes include:
-
- Thin Uterine Lining: When the lining of the uterus is too thin, it can affect the embryo’s ability to implant and grow.
- Surface Lesions in the Uterus: Polyps, fibroids, or scar tissue in the uterus can interfere with embryo implantation.
- Immunologic Implantation Dysfunction (IID): Sometimes, the immune system can mistakenly attack the embryo, preventing successful implantation.
- Endocrine/Molecular Endometrial Receptivity Issues: Hormonal or molecular issues in the uterine lining can impact the embryo’s ability to attach and develop.
- Ureaplasma Urealyticum (UU) Infection: This infection in the cervical mucous and uterine lining can lead to unexplained early pregnancy loss or IVF failure. Both partners should be tested and treated if positive to prevent transmission.
Certain causes of infertility are difficult or impossible to reverse, e.g.; advanced age of the woman, severe male infertility, and immunologic implantation dysfunction associated with certain specific genetic factors.
Understanding the common factors contributing to IVF failure can help you have informed discussions with your doctor and make decisions for future attempts. Factors like the number of embryos transferred and implantation dysfunction play significant roles. While success cannot be guaranteed, knowing these factors can guide you in maximizing your chances and addressing potential issues.
Â
Â
_____________________________________________________________
ADDITIONAL INFORMATION:
I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)……. for your reading pleasure:
1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “
https://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf
- “Recurrent Pregnancy Loss and Unexplained IVF Failure: The Immunologic Link
https://drive.google.com/file/d/1iYKz-EkAjMqwMa1ZcufIloRdxnAfDH8L/view
- If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or go to concierge@sherivf.com .
- Also, I have just started a new Podcast https://rumble.com/c/c-3304480. Feel free to take a look-see……… And please spread the word!
Hcg report
Name: Rupali S
My HCG level is 1.600.Is it Negative
Answer:
Yes! I am afraid this is a negative result!
GS
________________________________________________________________
ADDITIONAL INFORMATION:
I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)……. for your reading pleasure:
1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “
https://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf
- “Recurrent Pregnancy Loss and Unexplained IVF Failure: The Immunologic Link
https://drive.google.com/file/d/1iYKz-EkAjMqwMa1ZcufIloRdxnAfDH8L/view
- If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or go to concierge@sherivf.com .
- Also, I have just started a new Podcast https://rumble.com/c/c-3304480. Feel free to take a look-see……… And please spread the word!