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CASE REPORT: A woman in her Early 40’s who has Diminished Ovarian Reserve Requiring IVF with Embryo Banking and PGS.

Hi Dr Sher, I’m 42 years of age. Until very recently, I knew nothing
about IVF, and I now find myself in a scramble to optimize my chances
with it. Despite a lifelong dream of having a healthy baby and happy
family, it has taken me this long to find a great man/dad I can
believe in for my unborn kids, so prior, I always used protection and
never tried to get pregnant. Since my mom got pregnant naturally at
40, I grew up thinking that was normal-or at least normal for my
family. And, I …

CASE REPORT: A woman in her Early 40’s who has Diminished Ovarian Reserve Requiring IVF with Embryo Banking and PGS. Read More »

Defining and Addressing an Abnormal Luteal Phase

Following ovulation, what remains of the ruptured follicle transforms
itself into a structure called the Corpus Luteum (CL) which produces
progesterone. The purpose of progesterone is to prepare the uterus to
accept and support an early pregnancy until it is able to sustain
itself at around 8-10 weeks of gestation.
The life span of the CL is predetermined to be 12-13 days, unless
rescued by a signal from the early pregnancy. If no pregnancy occurs,
the CL …

Defining and Addressing an Abnormal Luteal Phase Read More »

“Unexplained” Infertility : Often a matter of the Diagnosis Being Overlooked!

For about 10% of all infertile couples, the cause of the infertility
cannot be readily determined using conventional diagnostic methods.
Such cases are often referred to as “unexplained infertility.” The
truth however is that in most such cases, the diagnosis of
“unexplained infertility is in fact presumptive because a more
in-depth evaluation would have revealed a cause. This having been
said, people diagnosed with so called “unexplained infertility”
fall into two broad groups: a)…

“Unexplained” Infertility : Often a matter of the Diagnosis Being Overlooked! Read More »

The Role of IVF in Cases of Tubal Damage

Tubal damage is one of the commonest causes of infertility. It is most
often due to pelvic inflammatory disease (PID)
[/blog/pelvic-inflammatory-disease-pid-tubal-damage-hydrosalpinx-preparing-ivf/]
caused by sexually transmitted bacterial infection with chlamydia
trachomatis and Neisseria gonorrhea. Acute PID caused by such usually
are associated with severe clinical manifestations such as rapid …

The Role of IVF in Cases of Tubal Damage Read More »

Ovarian Stimulation in Women Who have Diminished Ovarian Reserve (DOR): Introducing the Agonist/Antagonist Conversion protocol

The use of GnRH antagonists, as currently prescribed in ovarian
stimulation cycles
[/blog/optimizing-response-ovarian-stimulation-women-compromised-ovarian-reserve-personal-approach/],
i.e. the administration of 250mcg daily from the 6or 7th day of
stimulation with gonadotropins, is in my opinion problematic when used
in women who have

Ovarian Stimulation in Women Who have Diminished Ovarian Reserve (DOR): Introducing the Agonist/Antagonist Conversion protocol Read More »

Intralipid (IL) Administration in IVF Explained

Intralipid (IL)
[/blog/intralipid-ivig-therapy-treatment-immunologic-implantation-dysfunction/]is
a solution of small lipid droplets suspended in water. When
administered intravenously, IL provides essential fatty acids,
linoleic acid (LA), an omega-6 fatty acid, alpha-linolenic acid (ALA),
an omega-3 fatty acid. It is made up of 20% soybean oil/fatty acids
(comprising linoleic acid, oleic acid, p…

Intralipid (IL) Administration in IVF Explained Read More »

Prevention, Recognition, and Treatment of Hydatidiform Molar Pregnancies

A hydatidiform molar pregnancy [/blog/molar-pregnancy-treated/]
happens when tissue that normally forms the placenta instead becomes a
growth, that triggers symptoms of pregnancy. A hydatidiform mole is a
benign tumor of the root system (trophoblast) of the embryo which
under normal conditions develops into the placenta which connects the
baby to the mother. About 1 out of 2,000 women with early pregnancy
symptoms will have a molar pregnancy. I…

Prevention, Recognition, and Treatment of Hydatidiform Molar Pregnancies Read More »

IVF Pregnancy with a “Vanishing Twin”

Today, in first world environments where there is ready access to
advanced medical technology, many women undergo ultrasound diagnosis
of pregnancy as early as 5-6 weeks after their last menstrual period.
As a result, multiple pregnancies
[/blog/how-many-embryos-should-be-transferred-a-critical-decision-in-ivf/]
are often recognized very early on. Serial ultrasound follow-up
examinations performed in su…

IVF Pregnancy with a “Vanishing Twin” Read More »