Cyclical Estrogen Therapy Prior to Embryo Transfer, in Post-Menopausal Women and those with Prolonged Hypothalamic Amenorrhea, Can Reduce the Chance of Failed IVF and Miscarriage

by Dr. Geoffrey Sher | Nov 11, 2020 | Amenorrhea, Embryo, Estrogen, Gonadotropin, IVF, Thin Uterine

 An absence of menstruation (amenorrhea) in reproductive age women is usually due to an absence of ovulation (anovulation). If this becomes prolonged, then these women are at risk for the ill effects associated from chronically low estrogen levels...

Hormonal Supplementation in IVF

by Dr. Geoffrey Sher | Apr 24, 2020 | IVF, Ovarian Stimulation

Ovulation occurs within 38-42 hours of initiation of the spontaneous luteinizing hormone (LH) surge (which can be detected in the blood or urine prior to this event) and/or hCG administered following controlled ovarian stimulation (COS) with gonadotropins. One or more...

Are SART- Reported Clinic-specific, Annual IVF Outcome Statistics Reliable?

by Dr. Geoffrey Sher | Mar 5, 2019 | IVF, IVF Outcome, IVF Special Interest Group, SART, The Society for Assisted Reproductive Technology

IVF practitioners, and consumers have little reason to feel confident about the validity and reliability of SART published ART outcome statistics and here is how I reach this conclusion: About 30 years ago, I was a member of a steering committee charged by the...

IVF SUCCESS RATE EXPRESSED AS VIABLE PREGNANCY RATE PER EMBRYO TRANSFERRED (PRPE): A PROPOSED NEW PRADIGM FOR IMPROVED AND VERIFIABLE REPORTING OF IVF STATISTICS

by Dr. Geoffrey Sher | Dec 10, 2018 | Case Studies, Controversial Post, Failed IVF, Infertility, IVF

Given rapidly changing practices in the IVF arena, it is becoming increasingly implausible to reliably interpret current national reports expressing IVF outcome statistics as birth rate per initiated treatment cycle, per egg retrieval procedure or per embryo transfer...

Genetically Testing IVF Embryos

by Dr. Geoffrey Sher | Dec 3, 2018 | gender identification testing, Genetically Testing IVF Embryos, IVF, IVF Genetic Screening

Preimplantation genetic testing (PGT) involves testing pre-implantation embryos for chromosomal numerical abnormalities (aneuploidy). Preimplantation genetic diagnosis (PGD) involves genetic testing of embryos for specific genetic conditions. The objective of both PGT...

A Case for Transferring Blastocysts on Day 5-6 Post-Fertilization Rather Than on Day 2-3 as Cleaved Embryos.

by Dr. Geoffrey Sher | Nov 14, 2018 | IVF

Embryo transfer (ET) is undoubtedly the single most important step in IVF. It takes confidence, dexterity, skill and timing to optimally perform ET. Of all the procedures conducted in IVF, embryo transfer is the most difficult to perfect. Sadly, far too many women...