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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Search 1,006 questions patients have already asked, or narrow them by topic.

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  1. Ovarian Stimulation & OHSS

    Unsure about priming protocol estrace//ganarelix

    Hello Dr Sher, I am a scientist and as I often do i studied all mechanisms of action of IVF drugs. I have done natural start cycles but recently had leading follicles. AMH of 1.33 40 years old 6-9 afc… — Cecilia P.

    Dr. Geoffrey Sher answered

    There is so much to talk about. i think I can provide information that will be of help. I suggest you contact my assistant, Patti (702-533-2691) and set up an online consultation with me to discuss.. In the meanwhile,...see below. EGG/ EMBRYO QUALITY IN IVF & HOW SELECTION…

  2. Uterine & Endometrial Health

    FETcycle

    My previous FET cycle which was modified natural failed. It did not implant. my lining was only 7.2 mm so could have failed due to that. I was taking progesterone suppositories twice daily and on my day of transfer my… — Camila S.

    Dr. Geoffrey Sher answered

    The endometrial lining thickness is an issue but I do not think to progesterone administration is a factor...WE need to discuss this. I suggest you contact my assistant, Patti Converse (concierge@sherivf.com) and set up an online consultation with me. Geoff Sher FROZEN EMBRYO TRANSFER : ONE PREFERRED APPROACH…

  3. Uterine & Endometrial Health

    liningforFET

    how important is the trilaminar appearance before FET trigger? I am on a modified natural cycle and my RE put me on viagra PV to thicken my lining. at trigger my lining was 12.4mm but homogeneous. The sonographer told me… — Andreea N.

    Dr. Geoffrey Sher answered

    The3 trilaminar appearance is in my opinion not important.. An Ideal thickness is >9mm but >8mm is acceptable. Good luck! Geoff Sher

  4. Embryos & Genetic Testing

    Embryo Transfer

    Is it normal take 10mg Prednisolone 5 days before transfer and 5 Progynova a day? If so, do you have any suggested reasons why this might be the case ? Also how do you improve blood circulation prior to transfer?… — Meshelley S.

    Dr. Geoffrey Sher answered

    Respectfully, I do not uses such an approach! Geoff Sher

  5. Egg Health & Ovarian Reserve

    IVF

    I am 28 and my husband is 27. My husband was diagnosed with male factor infertility 1 year ago (low count, low motility). Our first IVF round produced 17 eggs, 14 mature, 14 fertilized and 6 untested fair quality blasts.… — Payton D.

    Dr. Geoffrey Sher answered

    I do not think the reason for your failed cycles was due to the male factor. It sounds more like an implantation dysfunction. We should connect online and discuss this in depth. I think I can help. Please call my assistant, Patti Converse at 702-533-2691 and set up…

  6. Embryos & Genetic Testing

    Opinion on french MatriceLab test

    Dear Dr. Sher, Thank you for the detailed article on immunological issues of embryo implantation failures. I'm writing to you as a fertility patient in France. After a certain number of blastocysts transfered with a single implantation and early miscarriage,… — Manon G.

    Dr. Geoffrey Sher answered

    I aplaud any research that serves to uncover the immunologic basis for implantation dysfunction. Endometrial local immunity is likely an important parameter that influences implantation and the the prognosis of pregnancy.. Diagnosis of an endometrial immune dysregulation . It seeks to assess embryo-endometrial interaction and focuses on several…

  7. Ovarian Stimulation & OHSS

    Agonist/Antagonist/Leuprolide

    Hi Dr. Sher, I loved your podcast with Dr. Aimee! I’m doing a3rd retrieval and had some thoughts/Q’s. I’m 36 years old, AMH 1.6. 1st retrieval 5 eggs - 3 mature - 3 fertilized - 2 euploid embryos. 2nd retrieval… — Grace D.

    Dr. Geoffrey Sher answered

    WE really should talk. I think I can both enlighten and help you. I am concerned by the low yield of eggs and think that the protocol used for ovarian stimulation should be evaluated and probably modified. I suggest that you call my assistant, Patti Converse (702-533-2691) and…

  8. Age & Fertility

    Ivf at 44

    Hello I’m contacting you to see if you offer ivf to age 44 to use my own eggs with my husband sperm. We are not having success with our current clinic. Please let us know. We live in Nebraska and… — Dana D.

    Dr. Geoffrey Sher answered

    Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…

  9. Ovarian Stimulation & OHSS

    Retrieval

    I’m almost ready to trigger for egg retrieval, but I only have four mature follicles. There are ten follicles total, but they didn’t mature at the same rate and my doctor won’t wait for those to mature because they only… — Ellen C.

    Dr. Geoffrey Sher answered

    Respectfully, I do not think this strategy is appropriate. Timing is everything in IVF. WE should talk. I suggest you call my assistant, Patti (702-533-2691). and set up an online consultation with me. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online…

  10. Social

    Where is the social media person that was there about two years ago? Is she still with you? I was starting my own business in fertility and I discussed working with SHER on a collaboration. She was so professional and… — Nancy V.

    Dr. Geoffrey Sher answered

    She left us!

  11. Embryos & Genetic Testing

    Recurrent implantation failures

    Dear Dr. Sher, Myself and husband are both 38 yrs old started our fertility journey at the age of 32 yrs so trying to conceive for 6 yrs now. We started with ovulation induction, had an ectopic treated with methotrexate.… — Remy A.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  12. Immunology & Implantation

    RIF

    Hi there, We had a son nearly 5 years ago within a few months of trying (cesarian), since then we have had a blighted ovum, 1 chemical pregnancy, 1 6 week miscarriage trisomy 8, and 10 failed implantations (of high… — Sean T.

    Dr. Geoffrey Sher answered

    This sounds very much like an anatomical implantation dysfunction (see below). I suggest we talk. Please contact my assistant, Patti Converse at 702-533-2691 to set this up. Geoff Sher IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES. Implantation dysfunction is often overlooked as a…

  13. IVF Failure & Pregnancy Loss

    Recurrent pregnancy loss

    Hi, I have RPL, and have 4 miscarriages this last year. Now done IVF with 13 eggs, 11 fertilized and only 2 made blasto at day 6. I have RA, mild endo. I take enbrel 50 mg 1xw and my… — Helene N.

    Dr. Geoffrey Sher answered

    When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…

  14. Embryos & Genetic Testing

    Vitrification of embryos

    Dear Dr. Sher, do you have experience with the freeze of day 4 embryos (morulas)? My clinic is suggesting that we freeze all remaining embryos on day 4 after transfer on same day, because day 5 is a Sunday and… — Cathryn L.

    Dr. Geoffrey Sher answered

    Frankly, I prefer to go to blastocyst just to have more confidence in embryo viability, however, transferring as morula isa acceptable. Geoff Sher Geoff Sher

  15. Immunology & Implantation

    Positive ANA

    Hi, I am ANA positive (as well as Smith (Sm) Ab, Sm RNP and Centromere B Ab Positive), I have had a chemical this year in March, a blighted ovum in June at 7 weeks, and then a MMC in… — Ashley A.

    Dr. Geoffrey Sher answered

    Thanks for connecting with me. I really think we should talk. Please read the material below and thereupon, call my assistant, Patti at 702-533-2691 and set up an online consultation with me to discuss! Geoff Sher IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES.…

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