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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Dr. Geoffrey Sher

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Hormones & Ovulation Aug 21, 2022

Carrier Requirements

Hello! I was wondering what requirements you have for the surrogates that your patients might work with if they choose the gestational surrogacy route. Is there an age limit or BMI limit? Would a surrogate who had diet-controlled gestational diabetes… — Jessi W.

Dr. Geoffrey Sher answered

Of course all the factors you mention and many more are part of the screening process. Also, I advocate that you meet with the surrogate. IVF surrogacy involves the transfer of one or more embryos into the uterus of a surrogate, who provides a host womb and carries…
Embryos & Genetic Testing Aug 19, 2022

FET protocol

Just wondering if you see any pitfalls in doing a simple oestrogen/progesterone protocol. I asked about adding in prednisolone, as a precaution. But the clinic is not keen using steroid medications- such as prednisolone, in patients who do not necessarily… — Cassidy C.

Dr. Geoffrey Sher answered

Perhaps we should talk! 702-533-2691
Embryos & Genetic Testing Aug 16, 2022

mosaic embryo

Good afternoon dear doctor! I am 42 years old, after 8 hormonal stimulations, I have a single mosaic embryo. Blastocyst 7 days. I need to decide an important question whether to transfer it or not. Embryo seq(3)x1~2,(6)x1~2. Mosaic monosomy of… — Olga M.

Dr. Geoffrey Sher answered

I would not advise using this embryo! Human embryo development occurs through a process that encompasses reprogramming, sequential cleavage divisions and mitotic chromosome segregation and embryonic genome activation. Chromosomal abnormalities may arise during germ cell and/or preimplantation embryo development and represents a major cause of early pregnancy loss.…
Infertility Basics Aug 15, 2022

fluconazole safety

Hello Dr Sher! I've taken this drug to treat thrush, 150mg. I'm getting my period is 8 days and am planning to start FET protocol - but I've since read that it's not a safe drug to take when trying… — Cassidy C.

Dr. Geoffrey Sher answered

THERE WOULD IN MY OPINION BE NO PROBLEM!
IVF Failure & Pregnancy Loss Aug 15, 2022

failed ivf

i'm 40 years old,my AHM is 0.89. i was undergoing an ivf which failed. they got 6 eggs,5 mature,i embryo was slowly groing ending up not sticking after transfering. later the doctir told me they examined my eggs and came… — Tammy S.

Dr. Geoffrey Sher answered

It is primarily the egg (rather than the sperm) that determines the chromosomal integrity (karyotype) of the embryo, the most important determinant of egg/embryo competency”. A “competent” egg is therefore one that has a normal karyotype and has the best potential to propagate a “competent” embryo. In turn,…
Hormones & Ovulation Aug 15, 2022

Hoshimoto’s question

Dear Dr. Sher, I've been following your comments for years. Thanks for the info. on 2 shots of Ovidrel. I'm interested in what you say here about Hoshimoto's and what you call "Immunologic Implantation Dysfunction." You mention that 50% of… — Katharine C.

Dr. Geoffrey Sher answered

I published on this 25y ago. Sher G, Maassarani G, Zouves C, Feinman M, Sohn S, Matzner W, Chong P, Ching W. "The use of Combined Heparin/Aspirin and Immunoglobulin G. Therapy in the Treatment of IVF Patients with Antithyroid Antibodies" Am J Repr Immunol, 1998; 39:223-5.
IVF Failure & Pregnancy Loss Aug 12, 2022

Ivf failure and suspect endometriosis

Hi Dr Sher I have been trying to conceive for 3 years now with no success. I've recently had 1 failed ivf cycle where I began bleeding 7 days post embryo transfer. Which I believe is implantation failure. I have… — Isma B.

Dr. Geoffrey Sher answered

often advised to first try ovarian stimulation (ovulation Induction) with intrauterine insemination (IUI) ………as if to say that this would be just as likely to result in a baby as would in vitro fertilization (IVF). Nothing could be further from reality It is time to set the record…
Hormones & Ovulation Aug 11, 2022

Hormone-producing simple cyst found at baseline scan

Dear Dr Sher, I recently had a baseline scan and oestrogen and progesterone blood tests for an upcoming FET cycle. The scan and blood tests identified a 2.5cm hormone-producing simple cyst on my left ovary. I have been prescribed 21… — Charlotte D.

Dr. Geoffrey Sher answered

Yes! It is likely to cause the functional cyst to absorb by the next period! An ovarian cyst is any collection of fluid, surrounded by a very thin wall, within an ovary. An ovarian follicle that is larger than 22mm is termed a functional follicular cyst. They are…
Embryos & Genetic Testing Aug 10, 2022

Embryo donation

We have an extra embryo to donate to another couple or science. What are our options? — Patrick R.

Dr. Geoffrey Sher answered

Please call 646-792--7476 and ask for Bushra Sudal RN. She will be glad to assist you.
Hormones & Ovulation Aug 10, 2022

Estradiol maximum levels before FET

Good day Dr. Geoffrey, I salute you from Mexico City. I'm in the mieddle of the preparatios for the FET, and I want to know what should the maximium estradiol levels be at the day before my FET. Today I'm… — Jimena A.

Dr. Geoffrey Sher answered

I prescribe twice weekly injections of estradiol valerate (Delestrogen). Using this approach, I aim for peak E2 values ranging between 500 and 1000pg/ml! Good luck!
Cost & Insurance Aug 9, 2022

Family Balancing

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Egg Health & Ovarian Reserve Aug 8, 2022

No normal embroys

Hi Dr. Sher, I am asking this question after first egg retrieval. I am 40 years old, first time doing this IVF. I saw about 23 follicles during ultrasound and was on 21 days lupron protocol ended with 20 eggs,… — Esther L.

Dr. Geoffrey Sher answered

The importance of the IVF stimulation protocol on egg/embryo quality cannot be overstated. This factor seems often to be overlooked or discounted by t IVF practitioners who use a “one-size-fits-all” approach to ovarian stimulation. My experience is that the use of individualized/customized COS protocols can greatly improve IVF…
Hormones & Ovulation Aug 4, 2022

Follicle Size – Immature at LH Surge?

Hi Dr. Sher, Just following up from my last question regarding my 14mm follicle on day 15 when I had a LH surge... isn't this too small of a follicle for a surge to happen meaning an immature/eggless follicle? I… — Elona K.

Dr. Geoffrey Sher answered

My response was based upon he suspicion that this 14mm follicle was actually 18mm + a day or so before and the reduction in size was due to partial ovulation.
Hormones & Ovulation Aug 4, 2022

Surge on day 15 with 14mm follicle

Hi Dr.Sher, I am doing an investigative cycle through my fertility clinic this month. Yesterday was my day 15 and on ultrasound I had a dominant follicle measuring 14mm. It was growing at a rate of 1mm per day since… — Elona K.

Dr. Geoffrey Sher answered

The most likely explanation is that when (on day 15 the 14mm follicle was seen, ovulation had already commenced!
Embryos & Genetic Testing Aug 4, 2022

Gender selection

Im looking to have a girl for my third pregnancy after having 2 boys. I have had no fertility issue and for both my kids I got pregnant in my first try. Do you have any gender selection service? Like… — Maryam F.

Dr. Geoffrey Sher answered

Couples have for centuries sought to influence the gender of their offspring. More than seven centuries ago the ancient Chinese developed a birth calendar said to be able to predict gender on the basis of when conception occurred. Later, the ancient Greeks suggested that by lying on her…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

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