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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Dr. Geoffrey Sher

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Hormones & Ovulation Feb 26, 2023

IVF failure 1x

I just went through my 1st IVF transfer on 2/15/23, I have found out I failed. My uterus lining was 9+ , Embryo was 4AA. I am wondering if it’s my natural killer cells. I had Endometriosis and a Septate… — Marisa T.

Dr. Geoffrey Sher answered

Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why! Was it simply due to, bad luck?, How likely is the failure to recur in future attempts and what can be done differently, to avoid it happening next time?.…
Immunology & Implantation Feb 26, 2023

Prednisone/Blood thinner

We are adding prednisone and Lovenox to my protocol next transfer. When is the best time to begin each of these- in relation to the transfer? For example, before transfer, day of transfer, after positive test? — K M.

Dr. Geoffrey Sher answered

10-14 days prior to transfer.! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “ http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf…
Early Pregnancy & hCG Feb 26, 2023

Pregnant

Can I drink pregomega plus along with clean and baby aspirin 17 weeks pregnant — Shoneez V.

Dr. Geoffrey Sher answered

Yes you can! Geoff sher
Uterine & Endometrial Health Feb 24, 2023

**correction ** progesterone levels after FET

I need to edit my previous post that my PIO dose was 50 mg once daily prior to FET then dropped to 12.5mg after P levels were checked day after FET — Lauren C.

Dr. Geoffrey Sher answered

Same answer! Geoff Sher
Uterine & Endometrial Health Feb 24, 2023

Progesterone levels after FET

Hi Dr SHER, my clinic’s FET protocol has me on both progesterone vaginal capsules 200mg 3x/day plus 100mg PIO once daily in preparation for FET. They tested my levels day before transfer and was good; they tested day after and… — Lauren C.

Dr. Geoffrey Sher answered

I strongly doubt any adverse effect! Good luck! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions…
Embryos & Genetic Testing Feb 24, 2023

Recurrent Miscarriage

After four losses (ages 23, 32, and 33) I was diagnosed with one copy of PAI-1 and one copy of MTHFR. I also have very high thyroid antibodies. Could all of this be causing the losses? We are moving on… — Mary P.

Dr. Geoffrey Sher answered

I doubt that the heterozygous PAI-1 and one copy of MTHFR can explain the losses. the thyroid antibodies is however another matter ...see below. Geoff Sher Between 2% and 5% of women of the childbearing age have reduced thyroid hormone activity (hypothyroidism). Women with hypothyroidism often manifest with…
Embryos & Genetic Testing Feb 23, 2023

Success after successful transfer

Hi! We just had our baby girl (4BB). Are the odds better doing a transfer for a second child since the first one worked? We had MFI and are 28! We transferred two embryos the first time (4AA & 4BB)… — Megan W.

Dr. Geoffrey Sher answered

I think your chance of success is good. I personally am willing to transfer up to 2 embryos at a time unless there is a specific obstetrics contraindication against twins. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my…
Ovarian Stimulation & OHSS Feb 21, 2023

Safety of Letrozole – Limit?

Hi Dr.Sher, Is there a limit to the number of letrozole cycles that one can do due to safety. I have done 12 cycles of letrozole. 8 of these have included using a trigger shot, Ovidrel. I know there are… — Kristin C.

Dr. Geoffrey Sher answered

In my opinion it is safe! However, that does not mean it is a judicious approach. Perhaps we should talk. I invite you to call my assistant Patti Converse at 702-533-2691 and set up an online consultation with me. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links…
Early Pregnancy & hCG Feb 21, 2023

Hcg level

Hello, My Hcg level on 25 January was 811 and now my Hcg level on 20 February is 14,328. I haven't had my first prenatal visit yet, but according to my app I'm supposed to be around 10 weeks pregnant.… — Briyah B.

Dr. Geoffrey Sher answered

My bet is that this is normal! Geoff Sher Measuring and interpreting Blood hCG to Assess Pregnancy Viability Following ART Treatments. Geoffrey Sher MD I know of no medical announcement associated with the degree of emotional anticipation and anguish as that associated with a pending diagnosis/confirmation of pregnancy…
Embryos & Genetic Testing Feb 21, 2023

Frozen embryo

We are planning to transfer our previous frozen embryo, and I did currently semen analysis and found uroplasma, do my wife need an antibiotic before transferring the frozen embryo, and if yes what is the antibiotic and what is the… — Yousef S.

Dr. Geoffrey Sher answered

Ureaplasma urealyticum is a bacterium that belongs to the mycoplasma family. It can be detected in the reproductive tract of as many as 40% of individuals (male and female). Ureaplasma probably does not prevent normal conception in the majority of cases, because by and large, the uterine cavity…
IVF Failure & Pregnancy Loss Feb 20, 2023

Ivf

Will m1 grade eggs fertilized? — Mahesh P.

Dr. Geoffrey Sher answered

Sometimes they do! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “ http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf “Recurrent Pregnancy…
Embryos & Genetic Testing Feb 16, 2023

Failed implantation

Hello, my husband and I have had a total of 6 good/top quality day 5 embryos implanted over the course of 2 years (2021- present). I have endometriosis, which I had surgery for in 2021. Following this surgery we had… — Ashley C.

Dr. Geoffrey Sher answered

Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss (RPL), and in women with underlying endo-uterine surface lesions, thickness of the uterine lining (endometrium) and /or immunologic factors. IVF success rates…
Embryos & Genetic Testing Feb 14, 2023

Failed cycles

Hi, I learned of your clinic today on the egg whisperer and several questions arose from that video. I’ve had one retrieval with six day 5 embryos. My first fresh transfer failed with no implantation and my second was a… — Mary E.

Dr. Geoffrey Sher answered

There is a possibility that the hydrosalpinges could be playing a role here. However, it is important to also consider the possibility of an anatomical and/or immunologic implantation dysfunction. Please read below and then, if you are interested, contact my assistant Patti Converse (702-533-2691) and set up an…
Clinic & Practice Feb 14, 2023

New Pathway without a referral

Hello, I was referred to you from great friends of mine and I’m already impressed that there is a question portal! My husband and I would like to change doctors and don’t have a referral. Would we need one to… — Deanna F.

Dr. Geoffrey Sher answered

I would be delighted to consult with you. Please contact my assistant, Patti Converse at 702-533-2691 and set up an online consultation with me. I look forward to meeting both you and your husband. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I…
IVF Failure & Pregnancy Loss Feb 13, 2023

Failed IVF Cycles

Hi Dr. Sher - I recently learned about you and your practice after listening to the Egg Whisperer Podcast. I've had two IVF cycles at two separate clinics in the Orlando, FL area. My first cycle resulted in 5 embryos,… — Ashley G.

Dr. Geoffrey Sher answered

Respectfully, This is likely NOT a lab issue but rather due to a combination of diminished ovarian reserve and the protocol used for ovarian stimulation. We should talk before you go any further. It is primarily the egg (rather than the sperm) that determines the chromosomal integrity (karyotype)…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

980 answers

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