– Geoffrey Sher, MD
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Embryos & Genetic Testing
Is it normal take 10mg Prednisolone 5 days before transfer and 5 Progynova a day? If so, do you have any suggested reasons why this might be the case ? Also how do you improve blood circulation prior to transfer?… — Meshelley S.
Dr. Geoffrey Sher answered
Respectfully, I do not uses such an approach! Geoff Sher
Egg Health & Ovarian Reserve
I am 28 and my husband is 27. My husband was diagnosed with male factor infertility 1 year ago (low count, low motility). Our first IVF round produced 17 eggs, 14 mature, 14 fertilized and 6 untested fair quality blasts.… — Payton D.
Dr. Geoffrey Sher answered
I do not think the reason for your failed cycles was due to the male factor. It sounds more like an implantation dysfunction. We should connect online and discuss this in depth. I think I can help. Please call my assistant, Patti Converse at 702-533-2691 and set up…
Embryos & Genetic Testing
Dear Dr. Sher, Thank you for the detailed article on immunological issues of embryo implantation failures. I'm writing to you as a fertility patient in France. After a certain number of blastocysts transfered with a single implantation and early miscarriage,… — Manon G.
Dr. Geoffrey Sher answered
I aplaud any research that serves to uncover the immunologic basis for implantation dysfunction. Endometrial local immunity is likely an important parameter that influences implantation and the the prognosis of pregnancy.. Diagnosis of an endometrial immune dysregulation . It seeks to assess embryo-endometrial interaction and focuses on several…
Embryos & Genetic Testing
Dear Dr. Sher, Myself and husband are both 38 yrs old started our fertility journey at the age of 32 yrs so trying to conceive for 6 yrs now. We started with ovulation induction, had an ectopic treated with methotrexate.… — Remy A.
Dr. Geoffrey Sher answered
Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Embryos & Genetic Testing
Dear Dr. Sher, do you have experience with the freeze of day 4 embryos (morulas)? My clinic is suggesting that we freeze all remaining embryos on day 4 after transfer on same day, because day 5 is a Sunday and… — Cathryn L.
Dr. Geoffrey Sher answered
Frankly, I prefer to go to blastocyst just to have more confidence in embryo viability, however, transferring as morula isa acceptable. Geoff Sher Geoff Sher
Egg Health & Ovarian Reserve
I’m at a bit of a loss. Having ICSI for secondary infertility (1st child conceived naturally age 29) and just midway through my 3rd cycle. I have paid up for a 4th cycle already so I’m keen to get some… — Amy E.
Dr. Geoffrey Sher answered
WE would need to discuss this complex matter. I suggest you call my assistant, Patti Converse (702-533-2691 and set up an online consultation with me. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my…
Embryos & Genetic Testing
What could cause a day 7 BB blastocyst that was fertilized via ICSI to be haploid (PGT-A results)? — Addison J.
Dr. Geoffrey Sher answered
It is likely "incompetent". Geoff Sher
Egg Health & Ovarian Reserve
Dear Dr. Sher: Thank you for hosting this forum. I am just shy of 41 with social infertility and have had two failed IVF cycles. The first used an antagonist protocol at 300 IU gonadotropin and resulted in one whole… — Claire C.
Dr. Geoffrey Sher answered
Please read what follows and thereupon, might I suggest that we talk . Please call my assistant. Patti at 702-533-2691 and set up an online consultation with me to discuss. The journey of in vitro fertilization can be a rollercoaster of emotions for many patients. Often times they…
Embryos & Genetic Testing
My fresh embryo transfer was canceled two days before the procedure due to a yeast infection (vaginal candidiasis), and I’m wondering why this infection may have occurred. I haven’t had sexual intercourse or done anything specific that I believe could… — Hannah A.
Dr. Geoffrey Sher answered
In my opinion there is no reason to cancel FET because of a yeast infection. Geoff Sher
Egg Health & Ovarian Reserve
Dear Dr. Sher. I am out of options i feel. Unknown fertility problem, endometriosis. I am now 30 years old. For the last 5 years: 5 IVF/ICSI cycles, 65 mature eggs, 30 fertilized, 0 good blastocyst, only poor quality, nothing… — Maggy M.
Dr. Geoffrey Sher answered
Embarking on the journey of IVF often raises questions about the likelihood of success and the quality of embryos. While it’s challenging to predict outcomes due to various factors, there’s hope and information to guide you. Firstly, the key to fertilization potential lies in the chromosomal integrity of…
Egg Health & Ovarian Reserve
Dear Dr. Sher, I am 43 years old, and in the last 2 years: 6 cycles, 100 follicles, 90 oocytes collected, 60 oocytes matured, 50 embryos, 10 blastocytes, 1 euploid. One abortion (prior to ivf), two failed transfers (the euploid… — Anne C.
Dr. Geoffrey Sher answered
I think we should talk first before you make that determination definitively. If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or email her at concierge@sherivf.com\ Geoff Sher ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF…
Embryos & Genetic Testing
Hello, I am a 32 y/o in Canada with history of 3 euploid miscarriages. First pregnancy embryo stopped growing 6.5 weeks, second pregnancy was a MMC of a blighted ovum, third pregnancy mono/mono twins resulted from a single embryo, both… — Anastasia S.
Dr. Geoffrey Sher answered
Respectfully, your immunologic implantation dysfunction is likely due to an alloimmune cause and if so would require different treatment (see below and read the E-books presented below ). I suggest you call my assistant, Patti Converse and set up an online consultation with me to discuss your case…
Embryos & Genetic Testing
Hi Dr. Sher, You did my egg retrieval 3 years ago, and we welcomed our beautiful daughter 2 years ago. We just did another transfer of 1 pgt embryo for a baby boy, and it failed. We only have 1… — Megan L.
Dr. Geoffrey Sher answered
We should talk. Please call my assistant, Patti (702-533-2691) and set up an online consultation to discuss. Geoff Sher
Embryos & Genetic Testing
Dear Dr Sher, I have listened with interest to your interviews on The Egg Whisperer and I hope you won’t mind my reaching out. I am a 46 year old woman from London, UK. I began IVF treatment with my… — Belle E.
Dr. Geoffrey Sher answered
There is no point in holding on to a "complex aneuploid embryo". You should discard it , in my opinion. There can be a very rapid decline in AFC at your age . This is because of inevitable decline in ovarian reserve and in egg quality. If you…
Embryos & Genetic Testing
I worked with you about 3 years ago. Thank you for helping us to our dream daughter. We are forever grateful. My question is about another embryo I would like to transfer . This is how it’s labeled, 46,XX,del(4)(q22). In… — Haley P.
Dr. Geoffrey Sher answered
Wonderful hearing from you...You made my day! I invite you to call 702-533-2691 and ask my assistant, Patti Converse, to set up an online consultation with me to discuss. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books…
