Third-Party Reproduction
donante
como puedo hacer para ser donante de ovulos — Barbara A.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
Ask Our Doctors
Supporting Your Journey
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
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Dear Patients,
I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.– Geoffrey Sher, MD
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Answers from our doctors
Search 1,006 questions patients have already asked, or narrow them by topic.
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Ovarian Stimulation & OHSS
Protocol Question
I am writing to ask for advice on the proper protocol for me. Background: I am 32 years old, with a normal BMI. My AMH is 0.11, and my AFC is 3. My husband has male-factor infertility that requires IVF.… — Avery C.
Dr. Geoffrey Sher answered
Respectfully, I do not think you were on optimal stimulation protocols. I suggest you call my assistant, Patti (702-533-2691)and set up an online consultation with me to discuss in detail. Understanding the impact of ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it…
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Embryos & Genetic Testing
Failed FET w/ Autoimmune disorder
Hello Dr. Sher, I listen to your podcast with Dr. Aimee Eyvazzadeh and I wanted to engage with you before going into another FET w/egg donor my questions to you: 5 year IVF Journey/History: * Zero pregnancy * 2 Aneuploid… — Rosalyn G.
Dr. Geoffrey Sher answered
Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
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Third-Party Reproduction
Mujer
Como puedo ser madre surrogada — Sandra A.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
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Embryos & Genetic Testing
Mosaic transfer
Hi!! I have a grade 422 low level mosaic. Specifically, it says 46, XY, -Yp (x0, mos, ~40%), -14 (x1, mos, ~50%). What are my real options to have a healthy/sick baby if I get it transferred? Thank you so… — Xiomara R.
Dr. Geoffrey Sher answered
Human embryo development is a marvel of intricate processes, including reprogramming, sequential cleavage divisions, mitotic chromosome segregation, and embryonic genome activation. However, the journey towards a successful pregnancy is not without its challenges, as chromosomal abnormalities can occur during germ cell and preimplantation embryo development, leading to early…
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Egg Health & Ovarian Reserve
Empty follicle
Dear Dr. Geoffrey, I get a empty follicle. What I can change for my last stimulation? Low AMH. Age 40. Kind regards, Charlene — Charlene T.
Dr. Geoffrey Sher answered
“Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely to happen when multiple attempts are needed to retrieve an egg from a follicle, indicating the egg may have chromosomal abnormalities. The…
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Ovarian Stimulation & OHSS
No concebir con omifin
Puedo volver a tomar clomid ahora que han pasado más de cuatro meses de descanso? — Iman D.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
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Third-Party Reproduction
Donación de óvulos
Cómo hago para ser donante de óvulos que requisitos debo cumplir para donar — Netzaly P.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
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Hormones & Ovulation
unexplained secondary infertilty
Dear Dr, my husband and I have a 5year old daughter. we have been trying to get pregnant for the last 4 years but no success so far. we visited a fertility Dr and were subjected to hormonal profile test,… — Clare A.
Dr. Geoffrey Sher answered
UNEXPLAINED” INFERTILITY: A RATIONAL APPROACH TO MANAGEMENT Infertility affects y 10%-15% of couples who are unable to conceive. In some cases, the cause of infertility cannot be determined using conventional diagnostic methods, leading to a diagnosis of "unexplained infertility." However, it is important to note that in most…
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Third-Party Reproduction
Donación de ovulos
hola, buen día. Quería saber cuantos años tengo que tener para donar óvulos y cómo sería todo el proceso, tengo que pagar algo? — Brenda N.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
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Cost & Insurance
FET inquiry
Hi, My wife and I are doing IVF in Canada and going to transfer embryos to United States for surrogacy. Can I know the cost estimation of FET at your clinic? (including fees to receive embryos from other clinics, FDA… — Ziyi W.
Dr. Geoffrey Sher answered
Please call Jessie at SFS in New York (646-792-7476) for this information. Geoff Sher
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Embryos & Genetic Testing
HLA matching
Hello, I compared the markers of different HLA genes between myself and my husband from our raw genetic data which was produced by 23andMe and I found the following: 1. HLA-A: 3/3 markers matched = 100% 2. HLA-B: 2/4 markers… — Holly S.
Dr. Geoffrey Sher answered
This is too complex for me to respond to authoritatively here. I request that you call my assistant, Patti Converse (702-533-2691) and set up an online consultation with me to discuss. Geoff Sher
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Embryos & Genetic Testing
Frozen Donor eggs and no blastocysts
Dear Dr. Sher, Im 37 years old with long story of 15 natural chemical pregnancies and after one ovarian stimulation with my oen eggs but with no blastocysts in October 2023 I decided to go through frozen donor eggs from… — Ola C.
Dr. Geoffrey Sher answered
I think we should talk. Please call my assistant, Patti Converse (702-533-2691) and set up an online consultation with me to discuss in depth. UNDERSTANDING RECURRENT PREGNANCY LOSS ( RPL): CAUSES AND SOLUTIONS. When it comes to reproduction, humans face challenges compared to other mammals. A significant number…
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Immunology & Implantation
Secondary Recurrent Pregnancy Loss and possible IID
Hi Dr Sher, I am 40 years old and have suffered with a number of early pregnancy losses in the past year, all conceived naturally. I have a 3 year old son who was conceived easily with no issues during… — Bronagh M.
Dr. Geoffrey Sher answered
When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
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Infertility Basics
RPL, Secondary Infertility
Hello Dr. Sher, I am experiencing my 4th biochemical pregnancy in less than 2 years. I am 45 years old with 8 previous live births. My youngest son turned 2 years old in January. I recently acquired Day 3 labs… — Faith R.
Dr. Geoffrey Sher answered
I am attaching an article I wrote on RPL but I would like to preface this by saying that at 45y of age, and especially with concomitant DOR, the large majority of your eggs will be aneuploid and resulting embryos too. Such embryos, if they implant will be…