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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Answers from our doctors

Search 1,006 questions patients have already asked, or narrow them by topic.

  1. Uterine & Endometrial Health

    Anatomy

    What is Inflammation of uterus — Ali-abbas M.

    Dr. Geoffrey Sher answered

    Endometritis where the endometrial lining becomes infected and inflamed, raising the possibility of an implantation dysfunction. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization…

  2. Uterine & Endometrial Health

    Thick uterine lining

    I usually have a thick lining and went in for US and it's already at 11 after 6 days of estrogen (one 0.10mg patch March 15 and changed the patch on Saturday to a new 0.10mg patch).. When I went… — Rennae F.

    Dr. Geoffrey Sher answered

    As long as there is no endometrial pathology there is no such thing as a "too thick" endometrium. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In…

  3. Egg Health & Ovarian Reserve

    IVF & Endometriosis

    37 yrs old, 1.6 amh. 7 years of infertility, 4 failed IUI's before surgery, 2 surgeries to remove endometriosis and endometriomas on both ovaries, 1 IVF completed and obtained one normal 5BB embreyo. What protocol is best for 2nd IVF… — Jule A.

    Dr. Geoffrey Sher answered

    ENDOMETRIOSIS AND IVF When women with infertility due to endometriosis seek treatment, they are all too often advised to first try ovarian stimulation (ovulation Induction) with intrauterine insemination (IUI) ………as if to say that this would be just as likely to result in a baby as would in…

  4. Uterine & Endometrial Health

    Progesterone dose and levels concern

    My doctor tested my progesterone (P) levels 1 day after 5 day transfer and said it was 103 (Canadian units) but that it should be 50-100. He dropped my dose from 50 mg PIO to 12.5 mg without rechecking it… — Lauren C.

    Dr. Geoffrey Sher answered

    The decision is between you and your treating RE. I might have done differently, but I doubt it will make a difference. Good luck! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD).......…

  5. Immunology & Implantation

    High Foxp3 T-Cells

    Hi Dr Sher, My Proliferative Phase Endometrium Immune Cell Studies on CD9 came back with Natural Killer Cells present at 5.1% and Foxp3 cells at 26/mm2. My fertility specialist has included in my next treatment plan for a FET for… — Katrina P.

    Dr. Geoffrey Sher answered

    I am sending you a copy of my book on immunology. You will see that I use a different approach for fixing on treatment. Geoff Sher Currently, with few exceptions, practitioners of assisted reproduction tend to attribute “unexplained and/or repeated” IVF failure(s), almost exclusively to poor embryo quality,…

  6. IVF Failure & Pregnancy Loss

    Multiple IVF fails

    Hi Dr. Sher thank you for your time. I’m 45 mother of 2 -18 &17 yr olds(normal pregnancies) I been doing IVF for the past 3 years. I’m currently on my 8th treatment with sperm & egg donor. I’ve had… — Ashley T.

    Dr. Geoffrey Sher answered

    Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why! Was it simply due to, bad luck?, How likely is the failure to recur in future attempts and what can be done differently, to avoid it happening next time?.…

  7. Hormones & Ovulation

    IVF failure 1x

    I just went through my 1st IVF transfer on 2/15/23, I have found out I failed. My uterus lining was 9+ , Embryo was 4AA. I am wondering if it’s my natural killer cells. I had Endometriosis and a Septate… — Marisa T.

    Dr. Geoffrey Sher answered

    Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why! Was it simply due to, bad luck?, How likely is the failure to recur in future attempts and what can be done differently, to avoid it happening next time?.…

  8. Uterine & Endometrial Health

    **correction ** progesterone levels after FET

    I need to edit my previous post that my PIO dose was 50 mg once daily prior to FET then dropped to 12.5mg after P levels were checked day after FET — Lauren C.

    Dr. Geoffrey Sher answered

    Same answer! Geoff Sher

  9. Uterine & Endometrial Health

    Progesterone levels after FET

    Hi Dr SHER, my clinic’s FET protocol has me on both progesterone vaginal capsules 200mg 3x/day plus 100mg PIO once daily in preparation for FET. They tested my levels day before transfer and was good; they tested day after and… — Lauren C.

    Dr. Geoffrey Sher answered

    I strongly doubt any adverse effect! Good luck! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions…

  10. Clinic & Practice

    New Pathway without a referral

    Hello, I was referred to you from great friends of mine and I’m already impressed that there is a question portal! My husband and I would like to change doctors and don’t have a referral. Would we need one to… — Deanna F.

    Dr. Geoffrey Sher answered

    I would be delighted to consult with you. Please contact my assistant, Patti Converse at 702-533-2691 and set up an online consultation with me. I look forward to meeting both you and your husband. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I…

  11. Ovarian Stimulation & OHSS

    Clomiphene

    Hi Dr. Sher, I am 42, trying for our 2nd baby. I had regular periods and ovulated well till October 2022 when My OB doctor prescribed Clomiphene x5 days. My cycles became mess after that. Periods last for 16-17 days,… — Iryna S.

    Dr. Geoffrey Sher answered

    Clomiphene (syn; Clomid , Serophene) is by far the most widely prescribed agent for the induction of human ovulation for women who do not ovulate, those with dysfunctional ovulation and women with ”unexplained” infertility. When used in young women (who have adequate ovarian reserve) with these problems the…

  12. Embryos & Genetic Testing

    Sonohysterogram during a FET

    Hi Dr Sher, do you believe its okay to get a Sonohysterogram done during cycle day 6 - 11 of a medicated Frozen Embryo Transfer cycle? Can the medication (Estrogen and Progesterone) interfere with the SHG results or vice-versa? — Jennifer L.

    Dr. Geoffrey Sher answered

    Respectfully! I personally would not perform a SNH during a cycle of FET! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A…

  13. Ovarian Stimulation & OHSS

    Thin uterine lining after egg retrieval

    Is it possible to have damaged the lining of my uterus during egg retrieval? My uterine lining went from 9.9mm 2 days before egg retrieval to 5mm after. Please advise. — Shernelle T.

    Dr. Geoffrey Sher answered

    That is highly unusual. The ER would not have caused this. Perhaps one of these measurements was not accurate. It was as far back as 1989, when I first published a study that examined the correlation between the thickness of a woman’s uterine lining (the endometrium), and the…

  14. Third-Party Reproduction

    Possible IVF egg donor and success for patients who have Adenomyosis and Endometriosis

    Hi We are based in the UK and want to know your live birth success rates for patients using egg donor, with a diagnosis of Adenomyosis and Endometriosis. I am also age 47 yrs and understand that there are risks… — Fiona F.

    Dr. Geoffrey Sher answered

    Adenomyosis-Related Infertility: A Therapeutic Challenge! Geoffrey Sher MD Adenomyosis is a condition where endometrial glands develop outside the uterine lining (endometrium), within the muscular wall of the uterus (myometrium). Definitive diagnosis of adenomyosis is difficult to make. The condition should be suspected when a premenopausal woman (usually>25 years…

  15. Uterine & Endometrial Health

    Plan for a Receptiva

    Hi I’m currently under the care of a Boston clinic (reside in Bermuda). I am considering transferring clinics and location but have one remaining embryo to transfer. Before doing so I would like a receptiva test carrying out for endometriosis.… — Gemma W.

    Dr. Geoffrey Sher answered

    It should not present a problem, in my opinion. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility…

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