Third-Party Reproduction
egg donation
I want to donate eggs, I've done it before — Judi F.
Dr. Geoffrey Sher answered
Please call Rozanne at "Footsteps to Family" (702-860-0097) for input. Geoff Sher
Ask Our Doctors
Supporting Your Journey
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
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Dear Patients,
I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.– Geoffrey Sher, MD
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Answers from our doctors
Search 1,006 questions patients have already asked, or narrow them by topic.
Latest answers
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Egg Health & Ovarian Reserve
Advice for last IVF round
Dear Dr. Sher: Thank you for hosting this forum. I am just shy of 41 with social infertility and have had two failed IVF cycles. The first used an antagonist protocol at 300 IU gonadotropin and resulted in one whole… — Claire C.
Dr. Geoffrey Sher answered
Please read what follows and thereupon, might I suggest that we talk . Please call my assistant. Patti at 702-533-2691 and set up an online consultation with me to discuss. The journey of in vitro fertilization can be a rollercoaster of emotions for many patients. Often times they…
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Immunology & Implantation
Infertility
Can you help me with infertility inmune issues — Susanna V.
Dr. Geoffrey Sher answered
Absolutely I can! Please call my assistant, Patti Converse (702-533-2691 or email her at concierge@sherfertility.com to set up an online consultation with me. Geoff Sher A RATIONAL BASIS FOR MANAGEMENT OF IMMUNOLOGIC CAUSES OF EMBRYO IMPLANTATION DYSFUNCTION In the world of assisted reproduction, when IVF fails repeatedly or…
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Embryos & Genetic Testing
FET canceled due to a yeast infection (vaginal candidiasis)
My fresh embryo transfer was canceled two days before the procedure due to a yeast infection (vaginal candidiasis), and I’m wondering why this infection may have occurred. I haven’t had sexual intercourse or done anything specific that I believe could… — Hannah A.
Dr. Geoffrey Sher answered
In my opinion there is no reason to cancel FET because of a yeast infection. Geoff Sher
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Egg Health & Ovarian Reserve
Adderall for DODR
Hello- I'm hearing a lot about the value of Adderall for patients with DOR and difficulty with implantation. Is there any data for this? What are the risks/benefits? Thank you! — Kristen S.
Dr. Geoffrey Sher answered
Respectfully, to my knowledge there is no data to support this. ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims…
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Egg Health & Ovarian Reserve
“Empty follicles”
Dr. Sher, I have a problem with my right ovary. Every time if we have more than one follicle > 17 mm in diameter on this side, we cannot retrieve the eggs (experienced that 3 times). We tried multiple protocols,… — Patricia K.
Dr. Geoffrey Sher answered
I suggest you call my assistant "Patti" (702-533-2691) and set up an online consultation with me to discuss...see below. EMPTY FOLLICLE SYNDROME” “Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely…
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Egg Health & Ovarian Reserve
Too many immature eggs
My daughter just completed her 2nd round of IVF. The first round yielded 7 out of 9 mature eggs but only one good blastocyst. This round yielded 14 eggs, and only 2 were mature. Only one of those fertilized &… — Eileen H.
Dr. Geoffrey Sher answered
Embarking on the journey of IVF often raises questions about the likelihood of success and the quality of embryos. While it’s challenging to predict outcomes due to various factors, there’s hope and information to guide you. Firstly, the key to fertilization potential lies in the chromosomal integrity of…
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Egg Health & Ovarian Reserve
Bad quality eggs
Dear Dr. Sher. I am out of options i feel. Unknown fertility problem, endometriosis. I am now 30 years old. For the last 5 years: 5 IVF/ICSI cycles, 65 mature eggs, 30 fertilized, 0 good blastocyst, only poor quality, nothing… — Maggy M.
Dr. Geoffrey Sher answered
Embarking on the journey of IVF often raises questions about the likelihood of success and the quality of embryos. While it’s challenging to predict outcomes due to various factors, there’s hope and information to guide you. Firstly, the key to fertilization potential lies in the chromosomal integrity of…
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Egg Health & Ovarian Reserve
It’s over
Dear Dr. Sher, I am 43 years old, and in the last 2 years: 6 cycles, 100 follicles, 90 oocytes collected, 60 oocytes matured, 50 embryos, 10 blastocytes, 1 euploid. One abortion (prior to ivf), two failed transfers (the euploid… — Anne C.
Dr. Geoffrey Sher answered
I think we should talk first before you make that determination definitively. If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or email her at concierge@sherivf.com\ Geoff Sher ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF…
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Immunology & Implantation
Alloimmunity Question
Hello Dr Sher. I received my fertilysis report stating that my husband and I are a full HLA-DQ match. I also have a moderately increased th1/th2 ratio. My NK cell cytotoxicity assay was normal. I have one living son followed… — Stephanie M.
Dr. Geoffrey Sher answered
Hard to say without direct access to your NK cell activity data in the Native state and to your and your partner's HLA/DQ alpha genotypes. I suggest you call my assistant, Patti (702-533-2691) and set up an online consultation to discuss. Also if you decide to do so,…
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Egg Health & Ovarian Reserve
poor egg quality
Im 37F no other medical history. AMH 2.01, Day 3 FSH 5.7, estradiol 56. Have done two cycles of IVF: First cycles I was on menopur (150) and gonal (initially 150 and bumped to 300) for about 11 days with… — Serena B.
Dr. Geoffrey Sher answered
In my opinion, you are young enough and have a normal ovarian reserve, such that egg quality should not likely be an inherent problem. In such cases, it is very often the protocol used for ovarian stimulation that plays a role here. It needs to be individualized to…
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IVF Failure & Pregnancy Loss
Hysteroscopy result
Hi, I have had 3 natural miscarriages, but 3 failed implantations with PGT embryos. I got a hysteroscopy, and they found dyssynchronous proliferative endometrium and polypoid dyssynchronous proliferative endometrium consistent with endometrial polyp. Can this have any impact in my… — Laura C.
Dr. Geoffrey Sher answered
UNDERSTANDING RECURRENT PREGNANCY LOSS ( RPL): CAUSES AND SOLUTIONS. When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending…
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Third-Party Reproduction
Donar óvulos
Hola quiero ser donante de óvulos — Andreina V.
Dr. Geoffrey Sher answered
Please Re-post in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility…
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Egg Health & Ovarian Reserve
IVF for Diminished Ovarian Reserve
I'm interested in speaking with only the best doctors as it relates my fertility. I look forward to speaking with you soon. I turned 49 recently. My odds of pregnancy with my own eggs are a long shot. I tell… — Teresa G.
Dr. Geoffrey Sher answered
At 49y, your only rql option is IVF with Egg donation....I am afraid, Geoff Sher IVF WITH EGG DONATION: A REVIEW Introduction: Egg donation is when a woman donates her eggs for assisted reproduction or research purposes. In assisted reproduction, it usually involves using IVF technology, where the…
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Egg Health & Ovarian Reserve
Low AMH, high AFC
I’ve been doing fertility treatments for five years. I have two kids. One with an IUI at age 35, one with IVF at 37. I’m now 40 and keep having trouble. My AMH is now .1, but my afc is… — Sara Q.
Dr. Geoffrey Sher answered
There is a high likelihood that aside from the age factor impacting egg quality, your severely diminished ovarian reserve sets you up fro what is known as "premature Luteinization". This is particularly more likely if the protocol used for ovarian stimulation is not optimally fashioned. ADDRESSING ADVANCING AGE…