Hello Dr Sher. I am a 34 yo F with spouse 43 yo M. G0P0, dx with unexplained infertility. BMI 22, no PMH and no male factors based on SA. Placed on levothyroxine during initial work up to bring TSH 7 mature —> 6 fertilized with ICSI –1 day 5 blast with PGT-A showing trisomy 16. We were told majority of embryos arrested at 8-10 cells pointing to an egg quality issue. IVF cycle 2 also 75 IU Menopur, 225 IU Follstim, Ganirelix CD7, dual trigger (Lupron with Pregnyl) with retrieval CD16. US day prior to trigger showed 36 follicles over 10 mm including 18 follicles over 15 mm with lead follicle 24.5 mm. 34 eggs retrieved–> 14 mature –> 11 fertilized w/ ICSI. Only two made it day 5 blast pending PGT-A. Husband & I are meeting with our REI to f/u this week. We are both physicians & willing to keep going with a few more cycles but I also want to be realistic on how many options there truly are for individuals with poor egg quality as we tried stimming longer and dual trigger and still only 2 made it to blast. Thank you in advance.