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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Embryos & Genetic Testing Aug 28, 2023

2 failed IVF frozen embryo transfers

Hello, I am 39 years old. I have now had 2 failed FET cycles. I’m getting frustrated bc my levels For everything have been “ideal” per my doctor and they are not sure why it is not working. I have… — Nikki F.

Dr. Geoffrey Sher answered

This sounds like an implantation dysfunction. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining…
IVF Failure & Pregnancy Loss Aug 22, 2023

IVF

I went in for I V F but I keep getting shiver and can not sleep — Bridget A.

Dr. Geoffrey Sher answered

See your RE and be evaluated to exclude ifection! Geoff Sher \ PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to…
IVF Failure & Pregnancy Loss Aug 22, 2023

Follicular study

On day 15th i went to follicular study and in right ovary egg size is 10.3×7mm and left ovary egg size is 10×6mm can I able to conceive doctor suggested me to come again on 24th for another follicular study — Lalitha I.

Dr. Geoffrey Sher answered

Possible but highly unlikely! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility…
IVF Failure & Pregnancy Loss Aug 21, 2023

Unknown ivf failure

I need to why it is happening ? — Juby B.

Dr. Geoffrey Sher answered

If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let's explore some common reasons for IVF failure in simpler terms.…
IVF Failure & Pregnancy Loss Aug 14, 2023

Miscarriage

Hello... My name is Claire...I've had 3 pregnancy losses ..one was at 6weeks and the rest were chemical pregnancies they exited even before I noticed I was pregnant..my gyna did thyroid.. diabetes and immune disorder test with my blood and… — Claire L.

Dr. Geoffrey Sher answered

When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Embryos & Genetic Testing Aug 12, 2023

Second hand infertility

Hi, I came across your podcast about implantation issues. I went thru infertility issues for 4 years (Ivf wasn’t covered) 19iuis- I had a miscarriage in the 2nd trimester- 3 chemical pregnancies and 2 miscarriages ending before 9 weeks we… — Lauren B.

Dr. Geoffrey Sher answered

Clearly you have recurrent pregnancy loss...likely due to an implantation dysfunction (anatomical or immunologic.However, I would need much more information to be able to comment authoritatively. When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not…
Embryos & Genetic Testing Aug 8, 2023

Balanced translocation & IVF Chemical Pregnancy

Hello Dr. Sher, After having two miscarriages (1 natural and 1 IUI), I found out that I have a robertsonian balanced translocation (13:14). My RE said that my best bet would be to do IVF with PGT-SR testing. I did… — Caitlin D.

Dr. Geoffrey Sher answered

The fact that the embryo transferred was euploid does not guarantee that it is was normal. There are genetic and metabolic factors that also can play a role. As for the low yield of "competent embryos, that likely has to do with the protocol used for ovarian stimulation.…
Infertility Basics Aug 7, 2023

Fertility options

My wife was diagnoses last year with Adenomyosis after having a miscarriage, and had a DNC. We've been having trouble getting pregnant ever since, and would like to know all options. We saw this on a show, and wondering if… — Adam L.

Dr. Geoffrey Sher answered

Adenomyosis is a condition where endometrial glands develop outside the uterine lining (endometrium), within the muscular wall of the uterus (myometrium). Definitive diagnosis of adenomyosis is difficult to make. The condition should be suspected when a premenopausal woman (usually>25 years of age) presents with pelvic pain, heavy painful…
Embryos & Genetic Testing Aug 5, 2023

RIF

Hello, I am a healthy, active 34 year old who has been trying to conceive for 5 years. I’ve had 5 PGT tested embryos transferred with 4 implantation failures and one a very low chemical. One healthy embryo and one… — Devan K.

Dr. Geoffrey Sher answered

Indeed, I often deal with cases such as yours. Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. In the pursuit of optimizing outcome with IVF, the clinician has a profound responsibility to meticulously assess and address this important issue if IVF success is…
Immunology & Implantation Aug 5, 2023

RE: Recurrent Miscarriages

Hello Dr. Sher I've been seeing Dr. Paschall here in Franklin TN, I believe she has been speaking with you about my case. I have had 20 missed/miscarriages over a 14 year span with my spouse but I have two… — LaPorche F.

Dr. Geoffrey Sher answered

When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
IVF Failure & Pregnancy Loss Aug 5, 2023

Follicular Analyses

Hi Sir, On 12th Day of period i have done TVS and one 30x23mm, one 16mm and 3/4 other smaller follicle on my right ovary. Will i be able to conceive with these? Thanks — Farjana Y.

Dr. Geoffrey Sher answered

The 30mm follicle is likely cystic and unlikely to house a good quality egg and the 16mm follicle is too immature to house a competent egg! Sorry! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY…
Egg Health & Ovarian Reserve Aug 1, 2023

IVF own eggs after failed attempt

Hello, I am considering treatment at a new clinic after a disappointing first attempt at IVF. I am 46 years old and tried using my own eggs. From my last blood test some two months ago I had an AMH… — Yasmin V.

Dr. Geoffrey Sher answered

You certainly could try again, but please know that age is a major factor affecting IVF outcome. Women over 44y of age are advised to do egg donation. Age should never be a barrier to hope and fulfillment when it comes to IVF. Many women in their early…
IVF Failure & Pregnancy Loss Jul 26, 2023

5 months pregnant but not detecting inupt test

Five months pregnant but not detecting on the UPT test — Aajay N.

Dr. Geoffrey Sher answered

_Something is not right! See your wife's OB to confirm that she is indeed carrying a viable pregnancy. Good luck! Geoff Sher I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In…
IVF Failure & Pregnancy Loss Jul 26, 2023

Down sydrome

My age is 30.i have a daughter 4 years old.she is perfectly fine..had a new born 26th june 2023 .she has down sydrome and moderate secudum asd..i used primolut N during 1st month of pregnancy because i didn't knew.can medicine… — Kanwal C.

Dr. Geoffrey Sher answered

To my knowledge, there is no established relationship! Geoff Sher I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “…
Age & Fertility Jul 19, 2023

Questions

Hi Dr Sher, I’m 43 yrs old & had a baby with IVF at 41 using the mini stim protocol (fresh) & hoping to try again for a 2nd. We’ve had 3 failed cycles since (using way higher doses). The… — Rosie S.

Dr. Geoffrey Sher answered

Frozen transfer of PGS-normal blastocyst is preferable in my opinion. With regard toi stimulation, consider the following: Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

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