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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Hormones & Ovulation May 30, 2023

Clomid

Hello, I was treated with Clomid day 5-9 and I am 36 years old. I failed to get pregnant 5 months and was prescribed this because of pcos. At the ultrasound at 12 days I had 4 mm endometrium and… — Erin K.

Dr. Geoffrey Sher answered

Clomiphene citrate (Clomid, Serophene) is the most popular agent used for inducing ovulation and in the 1980’s was also the most widely used method for COH in preparation for In Vitro Fertilization (IVF). Clomiphene citrate is a synthetic hormone that deceives the hypothalamus into thinking that the body's…
Embryos & Genetic Testing May 30, 2023

ZP1 mutation

Dr Sher My doctor says I have to undergo genetic testing to confirm if I have ZP1 mutation. My blood works and hormone level are within normal range. She says the eggs are killed before retrieval as there is abnormal/no… — Rana A.

Dr. Geoffrey Sher answered

Perhaps we should talk before you proceed along those lines . ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility…
Hormones & Ovulation May 30, 2023

Implantation issues h

Hi I’m 27 years old with lean pcos. I have had 2 good quality blastocyst transfers, both giving me faint BFP on 5 days past transfer which slowly goes to negative by 12-13 days past transfer. I don’t have endometritis,… — Saira I.

Dr. Geoffrey Sher answered

In the world of assisted reproduction, when IVF fails repeatedly or without explanation, it's often assumed that poor embryo quality is the main culprit. However, this view oversimplifies the situation. The process of embryo implantation, which begins about six or seven days after fertilization, involves a complex interaction…
Hormones & Ovulation May 30, 2023

Implantation issues h

Hi I’m 27 years old with lean pcos. I have had 2 good quality blastocyst transfers, both giving me faint BFP on 5 days past transfer which slowly goes to negative by 12-13 days past transfer. I don’t have endometritis,… — Saira I.

Dr. Geoffrey Sher answered

In the world of assisted reproduction, when IVF fails repeatedly or without explanation, it's often assumed that poor embryo quality is the main culprit. However, this view oversimplifies the situation. The process of embryo implantation, which begins about six or seven days after fertilization, involves a complex interaction…
Hormones & Ovulation May 24, 2023

Letrozole + HRT for ovulation induction

I am 40-year-old female trying to get pregnant. My estrogen levels and my AMH are rather low and my follicular phase very long of 27 days. Before going for IVF I am trying to improve my ovulation. My gynecologist gave… — Lucie M.

Dr. Geoffrey Sher answered

This is a very unconventional approach that I both do not advocate nor use. The protocol used for ovarian stimulation in women with DOR is very important. Consider the following: It is primarily the egg (rather than the sperm) that determines the chromosomal integrity (karyotype) of the embryo,…
Hormones & Ovulation May 22, 2023

PCOS But regular period

Hi Dr Sher I am diagnosed with pcos but my cycles are regular but I was not able to conceive despite trying for 2 years. After every ovulation my basal body temperature increased and progesterone also increased ( my gynecologist… — Teresa M.

Dr. Geoffrey Sher answered

I need much more information to provide an authoritative response . Please call my assistant, Patti at 702-533-2691 and set op an online consultation with me to discuss. ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew…
Egg Health & Ovarian Reserve May 18, 2023

Question-LH -short protocol-Metformin

Dear doctor, I am 35 years old, have gone through 8 ivf cycles, no pregnancy. At beginning e2 92, fsh 7,1, lh 9.5, amh 1.39. No PCOS. Early regrutation, I suppose DOR. From the start poor response on short protocol,… — Tamara I.

Dr. Geoffrey Sher answered

WE should talk! Feel free to call my assistant Patti Converse to set up an onloine consultation. Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why! Was it simply due to, bad luck?, How likely is the failure…
Hormones & Ovulation May 12, 2023

High prolactine level, infertility, anemia and fibrosis

Hi! I have tried to conceive for years, but the challenge has been a significant prolactin level that tablets could not reduce, even after swallowing for years. I did a couple of tests and I am told the prolactin is… — Gwaliwa M.

Dr. Geoffrey Sher answered

We should talk. If interested, please contact my assistant, Patti Converse at 702-533-2691 to set up an online consultationGeoff Sher Prolactin is a protein hormone (closely related to human growth hormone) that is secreted by specialized cells in the anterior part of the pituitary gland. In addition, the…
Hormones & Ovulation Apr 28, 2023

Rising progesterone before starting PIO in transfer cycle

Hi Dr Sher, I hope you're well. I'm so glad to see you are still doing this forum! Your advice helped me tremendously three years ago when I embarked on my first (successful) FET. I'm about to embark on my… — Rhian T.

Dr. Geoffrey Sher answered

Respectfully, I do all my FETs under hormonal control. That avoids such issues. Until less than a decade ago, most women undergoing IVF would have embryos transferred to the uterus in the same cycle that the egg retrieval was performed (“Fresh” Embryo Transfer). This was because embryo cryopreservation…
Hormones & Ovulation Apr 26, 2023

Am I ovulating?

I came off my pill in 2019 conceived within 4 months and had a beautiful daughter in 2020. I went back on the pill sep 2020. I came off the pill again in 2022 end of June. My cycles have… — Katelyn S.

Dr. Geoffrey Sher answered

_IT IS VERY LIKELY THAT YOU ARE NOT OVULATING FUNCTIONALLY! YOU SHOULD SEE YOUR OB/GYN ABOUT THIS. GEOFF SHER ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro…
Egg Health & Ovarian Reserve Apr 26, 2023

low immature oocytes

Hello, I have recently had a failed IVF cycle, and I think it might be due to the lupron being used as a trigger shot. I am 34, healthy, non smoker, active. We are doing IVF due to mail fertility… — Rana N.

Dr. Geoffrey Sher answered

Very respectfully, I must agree that the protocol used for ovarian stimulation was likely an issue here. I think we need to talk . Please contact my assistant, Patti Converse at 702-533-2691 and set up an online consultation with me. Regards, Geoff Sher The importance of the IVF…
Embryos & Genetic Testing Apr 21, 2023

Hormones and Genetics

Hello Dr, Sher! I am actually a result of your work back in 2002 with a couple, Vitaly and Svetlana Korchevsky. For years they had simply gotten the unexplained answer from doctors but with your help, I was born. Now… — Anna P.

Dr. Geoffrey Sher answered

Hi Anna, Wow! Thank you for sharing! Anna, I suggest you contact my assistant, Patti Converse (PH: 702-533-2691; email: concierge@sherivf.com) and set up an online consultation with me. G-d bless! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my…
Egg Health & Ovarian Reserve Apr 12, 2023

low immature oocytes

Hello, I had a failed IVF cycle. I am 34, healthy (No smoking, healthy diet, yoga 3 times a week), BMI 22 and doing IVF due to male infertility reasons. My Dr gave me the short protocol, my body responded… — Rana N.

Dr. Geoffrey Sher answered

I do not believe that this is likely to be due to an intrinsic egg issue. It is likely due to the type of protocol used and/or the type and typing/dosage/timing of the "trigger". We really need to talk. I suggest you call my assistant, Patti Converse at…
Hormones & Ovulation Apr 3, 2023

Infertility

Hi doctor, I am 30 years old, I have been diagnosed as PCOS , I received 12 cycle ovulation induction by clomid and letroze ,I did not conceived, last time I did ICSI , they told me that the eggs… — Sary A.

Dr. Geoffrey Sher answered

Polycystic ovary syndrome (PCOS) is a common hormonal system disorder among women affecting between 5% and 10% of women of reproductive age worldwide. Women with PCOS may have enlarged ovaries that contain small collections of fluid — called follicles — located in each ovary as seen during an…
Egg Health & Ovarian Reserve Mar 25, 2023

Am I a lost cause?

Dear doctor Sher, I am 33 years old and my husband is 36. After 5 months of trying to conceive (that was back in November 2022), we decided to visit a fertility specialist in Switzerland where we are currently located.… — Alexandra C.

Dr. Geoffrey Sher answered

Hi Alexandra, Yes indeed, based on your AMH blood level, you have prematurely developed diminished ovarian reserve (DOR) and this means you have very much reduced egg population (which cannot be replenished) and accordingly will propagate very few follicles. In addition, women with DOR often have an adverse…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

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