by Dr. Geoffrey Sher | Jul 24, 2023 | Endometriosis, Endometrium, Failed IVF, IVF, Thin Uterine, Uterus, Vaginal Viagra, Women
Back in 1989, I conducted a study that examined how the thickness of a woman’s uterine lining, known as the endometrium, affected the successful implantation of embryos in IVF patients. The study revealed that when the uterine lining measured less than 8mm in...
by Dr. Geoffrey Sher | Jun 9, 2023 | Age and Fertility, Blastocysts, Chromosomes, Controlled ovarian Stimulation (COS), COS, Diminished Ovarian Reserve, Diminished Ovarian Reserve (DOR), DOR, egg competency, Egg Quality, Embryo, Embryo Incompetency, Failed IVF, interpreting Blood hCG, IVF, IVF and blood hCG, IVF Failure, IVF for older women, IVF Outcome, OHSS, ovarian reserve, Ovarian Stimulation, Stimulation
The journey of in vitro fertilization can be a rollercoaster of emotions for many patients. Often times they have to face the harsh reality that the number and quality of eggs retrieved has fallen short of their expectations. Then, should fertilization of these eggs...
by Dr. Geoffrey Sher | Apr 25, 2023 | Alloimmune, Alloimmune Implantation Dysfuction, Autoantibodies, Autoimmune, Embryo, Embryo Incompetency, Endometriosis, Endometrium, Failed IVF, IID, Immunologic, Immunologic Implantation Dysfunction, Immunology, Implantation, Intralipid, IVF, IVF Failure, NKA, Pregnancy Loss, Vaginal Viagra
Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss (RPL), and in women with underlying endo-uterine surface lesions, thickness of...
by Dr. Geoffrey Sher | Apr 17, 2023 | Failed IVF, HLA, IID, Immunologic Implantation Dysfunction, Immunology, Implantation, Infertility, IVF Failure, KIR, MHC, NKA
I constantly receive inquiries from “confused” patients with unexplained recurrent IVF failure, unexplained infertility, recurrent pregnancy loss etc. (where an immunologic implantation dysfunction (IID) is often underlying) as to the relevance of measuring Killer...
by Dr. Geoffrey Sher | May 7, 2019 | Failed IVF
The blastocyst and the endometrium are in a constant state of cross-talk. In order for successful implantation to take place, the blastocyst must be at the appropriate stage of development, and needs to signal a well synchronized endometrium to ‘accept it”. This...
by Dr. Geoffrey Sher | Dec 10, 2018 | Case Studies, Controversial Post, Failed IVF, Infertility, IVF
Given rapidly changing practices in the IVF arena, it is becoming increasingly implausible to reliably interpret current national reports expressing IVF outcome statistics as birth rate per initiated treatment cycle, per egg retrieval procedure or per embryo transfer...
