IVF: How do you decide how many embryos to transfer?
The majority of IVF patients intuitively recognize that the more embryos transferred the greater will be the chance of their getting pregnant. However in…
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Ten years of writing on IVF, fertility and reproductive medicine from Sher Fertility Solutions. Ten years of writing on IVF and fertility.
Evaluation of IVF Outcome does not readily lend itself to “Evidence-Based Scientific Scrutiny”
The dictionary defines “evidence based medicine” as follows: “The practice of medicine in which the physician finds, assesses, and implements methods of diagnosis and…
The “Biological Clock” and How it Should Influence the Selection and Design of Ovarian Stimulation Protocols for IVF
It is inevitable reality that all women will at some point or another, experience a progressive decline in their reproductive potential. This occurs as…
PGT IN IVF: Some embryos that test PGT- chromosomally abnormal can self- correct in the uterus: Are we wrongly discarding embryos that are capable of developing into healthy babies?
Human embryo development occurs through a process that encompasses reprogramming, sequential cleavage divisions and mitotic chromosome segregation and embryonic genome activation. Chromosomal abnormalities may…
Micro-IVF: Often Preferable to Ovarian Stimulation with or Without IUI
Micro-IVF differs from “conventional IVF” in that when performed on younger women (2.0ng/ml and basal FSH=
IVF for Same Sex Couples
Gay, lesbian, or transgender individuals experience the same fears as any individual in the world. One of these is trepidation that they might not…
Immunologic Implantation Dysfunction: Importance of Meticulous Evaluation and Strategic Management: (Case Report)
Greetings Dr. Sher! Just wanted to first thank you for all that you do for women and infertility and I’m truly amazed and grateful…
IVF for Women Who Have Previously Conceived (Secondary Infertility)
While _Primary infertility_ refers to the inability of a woman who has never been pregnant in the past, to conceive, _Secondary Infertility_ is defined…
Sperm DNA Damage- Tests and Interpretation
THE SPERM CHROMATIN STRUCTURE ASSAY (SCSA): A MEASURE OF THE POTENTIAL OF SPERM TO HELP PROPAGATE A VIABLE PREGNANCY In about 40% of infertility…
Measuring and interpreting Blood hCG to Assess Pregnancy Viability Following ART Treatments
I know of no medical announcement associated with the degree of emotional anticipation and anguish as that associated with a pending diagnosis/confirmation of pregnancy…
Autism and Reproduction
Autism Spectrum Disorder (ASD) encompasses a range of conditions that most commonly affect males and are characterized by lifelong neurodevelopmental derangements manifesting as deficiencies in…
IVF Failure and Implantation Dysfunction: The Role of Endometrial Thickness, Uterine Pasthology and Immunologic Factors
The considerable emotional, physical and financial burden associated with infertility treatment in general and with IVF in specific, demand that factors known to affect…
Ovarian Stimulation For Women with Diminished Ovarian Reserve (DOR) and in Older Women undergoing IVF
Two main factors determine the quality of a woman’s eggs at ovulation or egg retrieval. First is her age and second is the protocol…
Fertility Drugs for IVF: How safe are They and do They Cause Cancer?
Are unsuspecting infertile women at increased risk through the drugs and treatment they administered with fertility treatment? When it comes to fertility drugs (e.g.…
The Role of Gender Selection: The Pros and Cons
Couples have for centuries sought to influence the gender of their offspring. More than seven centuries ago the ancient Chinese developed a birth calendar…
The BCP: Does Launching a Cycle of Controlled Ovarian Stimulation (COS) Coming off the BCP Compromise Response?
One often hears the expressed opinion that the BCP suppresses response to ovarian stimulation. This is not the case, provided that the BCP is…
Intrauterine Insemination (IUI): Who needs it and who does not; Pros and Cons
“As physicians we really need to seriously rethink the basis upon which we recommend IUI!” -GS Intrauterine insemination (IUI), the injection of sperm into…
Unexplained IVF Failure 2
When confronted with “unexplained” IVF failures where morphologically good embryos were transferred, the question arises as to whether the problem is due to inherent…
Egg Freezing: Fertility Preservation (FP) & Commercial Donor Egg Banks
The bottom line is that because of the traumatic effect of freezing on egg viability and “competency” the statistical chance of each frozen/ thawed…
Advantages of Combining Preimplantation Genetic Sampling (PGS) with Tests for Immunologic Implantation Dysfunction (IID)
Whenever IVF fails to resolve reproductive failure, the explanation is almost invariably either: a) embryo “incompetence” (usually …although not always due to the embryo…