The question
31 F/ G2 T0 P1 A1 L1/5’2.5 103lbs.
Diagnosis: functional hypothalamic amenorrhea. DOR/PCOS/Lactational/thyroid all ruled out.
Background: Past successful pregnancy with letrozol at 114lbs. Have been struggling with HA since then for 12 months. Past OBGYN wanted weight closer to 110lbs, gained to 107lbs and still had no ovulation so letrzol again to at 2.5mg. Conceived. Progesterone high at 37 on 6 days post ovulation. Miscarried due to blighted ovum. Am back down to 103lbs.
Question: Does the hormonal profile of a woman with HA contribute to low egg quality or poor embryo quality? Is my weight too low for safe pregnancy? Also have short cervix. Will low weight make that worse?
Answer from Dr. Geoffrey Sher
Women with HA can experience poorer egg quality. In addition, the low ovarian estrogen output can blunt endometrial response to estrogen. I advise you to have your doctor monitor endometrial thickness at the time of the hCG "trigger". It should measure at least 8mm. If less, this could signal an implantation dysfunction that would require treatment.
Good luck!
Geoff Sher
____________________________________________________________________________________________________________________
Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure:
- From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ; https://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf
- Recurrent Pregnancy Loss and Unexplained IVF Failure: The Immunologic Link ;https://drive.google.com/file/d/1iYKz-EkAjMqwMa1ZcufIloRdxnAfDH8L/view
If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or email her at concierge@sherivf.com\
General information only, not medical advice for your own situation. For that, book a consultation.